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Safety Information

S8432

Sigma-Aldrich

Sulfo NONOate disodium salt

Synonym(s):

Hydroxydiazenesulfonic acid 1-oxide disodium salt

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About This Item

Linear Formula:
N2O5SNa2
Molecular Weight:
186.06
MDL number:
MFCD01310974
UNSPSC Code:
12352200
PubChem Substance ID:
24899791
NACRES:
NA.77

form

powder

shipped in

dry ice

storage temp.

−70°C

SMILES string

[Na+].[Na+].[O-]\N=[N+](/[O-])S([O-])(=O)=O

InChI

1S/H2N2O5S.2Na/c3-1-2(4)8(5,6)7;;/h3H,(H,5,6,7);;/q;2*+1/p-2/b2-1+;;

InChI key

LYIIGAIVRHASTQ-SEPHDYHBSA-L

Application

Does not release NO; useful as a negative control in NONOate research

Biochem/physiol Actions

SKI 5C was used to inhibit Sphingosine kinase 1 in SK-Hep1, HEK-293T cells.1

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

S8432-50MG-PW:
S8432-BULK:
S8432-50MG:
S8432-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Aneta Balcerczyk et al.
Free radical biology & medicine, 39(3), 327-335 (2005-07-05)
The specificity of 4-amino-5-methylamino-2',7'-difluorofluorescein (DAF-FM) for nitric oxide was evaluated in in vitro systems. The probe was found fairly specific for nitric oxide. Potential sources of artifacts include the autoxidation of DAF-FM, potentiated by light, and its oxidation by sources
C M Maragos et al.
Journal of medicinal chemistry, 34(11), 3242-3247 (1991-11-01)
Selected nucleophile/nitric oxide adducts [compounds which contain the anionic moiety, XN(O-)N = O] were studied for their ability to release nitric oxide spontaneously in aqueous solution and for possible vasoactivity. The diversity of structures chosen included those in which the

Articles

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

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