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S1764

Sigma-Aldrich

Complement sera human

lyophilized powder

Synonym(s):

Human Serum Complement

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About This Item

MDL number:
MFCD00130855
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

human

Quality Level

200

form

lyophilized powder

origin

USA origin

technique(s)

cell culture | mammalian: suitable

impurities

virus, tested

shipped in

dry ice

storage temp.

−20°C

General description

Complement serum is prepared from pooled human plasma and lyophilized from the amount of serum indicated on the label.

Application

Complement sera human has been used:
  • to incubate DLD-1 or SW-620 cells to quantify C5a release
  • in multiplex bead antibody-binding assay to assay C3d
  • in complement-dependent cytotoxicity assay

Complement sera human has been used:
  • to incubate DLD-1 or SW-620 cells to quantify C5a release
  • in multiplex bead antibody-binding assay to assay C3d
  • in complement-dependent cytotoxicity assay

The activity of complement sera can be determined by hemolytic assays in vitro.

Physical form

Lyophilized powder from indicated amount of serum

Analysis Note

Hemolytic titer (CH50 units per ml) is determined by method of Kabat and Mayer. Actual titer given on label.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

S1764-VAR:
S1764-5X1ML:
R9130-1MG-PW:
S1764-1ML-PW:
S1764-BULK:
S1764-PH:
S1764-1ML:
S1764PROC:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cancer immunology research, 8(10), 1300-1310 (2020-09-03)
The programmed cell death protein 1 receptor (PD-1) and programmed death ligand 1 (PD-L1) coinhibitory pathway suppresses T-cell-mediated immunity. We hypothesized that cotargeting of PD-1 and PD-L1 with a bispecific antibody molecule could provide an alternative therapeutic approach, with enhanced
Chiaki Kawabata et al.
Biological & pharmaceutical bulletin, 44(2), 219-224 (2021-02-02)
Baculovirus vectors (BVs) are safely able to transduce foreign genes and express them in mammalian cells. However, the transduction activity of BVs is strongly reduced by the attack of serum complement, which is one of the major obstacles in the
S Nowicki et al.
Infection and immunity, 63(12), 4790-4794 (1995-12-01)
Human C1q displayed a dose-dependent protection of gonococcal cells (GC) from the bactericidal effect of newborn rat serum. All rat pups injected with C1q-preincubated GC developed bacteremia, while none of the animals injected with GC only were infected. After clearance
Anaïs Thiriard et al.
Frontiers in immunology, 14, 1107156-1107156 (2023-04-04)
To comprehensively analyze the quality of the antibody response between children with Multisystem inflammatory syndrome (MIS-C) and age-matched controls at one month after SARS-CoV-2 exposure, and infected in the same time-period. Serum from 20 MIS-C children at admission, and 14
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