Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

Safety Information

RES1000A-A7

SAFC

ACES

Synonym(s):

ACES, N-(2-Acetamido)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)taurine

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
H2NCOCH2NHCH2CH2SO3H
CAS Number:
7365-82-4
Molecular Weight:
182.20
Beilstein:
2253770
EC Number:
230-908-4
MDL number:
MFCD00008030
UNSPSC Code:
12352200
NACRES:
NA.21

biological source

synthetic

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin and microbial; tested

useful pH range

6.1-7.5

pKa (25 °C)

6.8

mp

>220 °C (dec.) (lit.)

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

NC(=O)CNCCS(O)(=O)=O

InChI

1S/C4H10N2O4S/c5-4(7)3-6-1-2-11(8,9)10/h6H,1-3H2,(H2,5,7)(H,8,9,10)

InChI key

DBXNUXBLKRLWFA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

ACES is a biological buffer often referred to as a “Good′s” buffer. The pKa of ACES is 6.8 which makes ACES a good candidate for a wide array for biological applications. ACES has been used primarily as a buffer in agarose and polyacrylamide gel electrophoresis separations as well as isoelectric focusing of proteins. ACES is highly water soluble and provides high-solution clarity.

Specific applications include buffers for cell culture media, protein separations and diagnostic reagent production.

Packaging

Product is available in the following package sizes:
RES1000A-A701X: 100 gm container
RES1000A-A702X: 1 kg container
RES1000A-A704X: 10 kg container

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

RES1000A-A702X:
RES1000A-A701X:
RES1000A-A704X:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
CDBF2146
CDBF2147
CDBD6524
CDBD5950
CDBD5951

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

D J Chappell
Clinical chemistry, 31(8), 1384-1386 (1985-08-01)
The hereditary deficiency variants of alpha 1-antitrypsin that are associated with diseases such as emphysema are usually identified by use of isoelectric focusing on polyacrylamide gels. Agarose is a simpler, faster, safer, and more reliable medium for this, but resolution
COMET challenges paradigm of ACE inhibition in mild heart failure.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners, 14(4), 207-208 (2003-11-19)
A Alonso
Electrophoresis, 10(7), 513-519 (1989-07-01)
The polymorphism of alpha-1-antitrypsin (PI) has been studied by hybrid isoelectric focusing in miniaturized immobilized pH gradient gels, with an interelectrode distance of 55 mm, in two narrow ranges of pH 4.35-4.75 and 4.35-4.55), following rehydration with pH 4.2-4.9 carrier
Free metal ion depletion by "Good's" buffers. II. N-(2-acetamido)-2-aminoethanesulfonic acid (ACESH): complexes with calcium(II), magnesium(II), manganese(II), cobalt(II), zinc(II), nickel(II), and copper(II).
J M Pope et al.
Analytical biochemistry, 103(2), 214-221 (1980-04-01)
P H Edelstein et al.
Journal of clinical microbiology, 31(12), 3329-3330 (1993-12-01)
Growth of Legionella spp. on buffered charcoal yeast extract medium supplemented with alpha-ketoglutarate and formulated with 3-(n-morpholino)propanesulfonic acid (MOPS), 3-(n-morpholino)-2-hydroxypropanesulfonic acid (MOPSO), or n-(2-acetamido)-2-aminoethanesulfonic acid (ACES) buffer was similar. With three exceptions, growth was no different in buffered yeast extract
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service