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R7502

Sigma-Aldrich

Roridin A from Myrothecium sp.

powder, ≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C29H40O9
CAS Number:
14729-29-4
Molecular Weight:
532.62
EC Number:
238-783-8
MDL number:
MFCD00055569
UNSPSC Code:
12352200
PubChem Substance ID:
24899393

Assay

≥98% (TLC)

form

powder

solubility

chloroform: ≥10 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(O)C1OCCC(C)C(O)C(=O)OCC23CCC(C)=CC2OC4CC(OC(=O)\C=C\C=C\1)C3(C)C45CO5

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300

Precautionary Statements

P264 - P301 + P310

Hazard Classifications

Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

R7502-5MG:
R7502-BULK:
R7502-VAR:
R7502-25MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J J Pestka et al.
Toxicology letters, 41(3), 215-222 (1988-06-01)
The effect of in vitro exposure to the macrocyclic trichothecenes roridin A and verrucarin A on human lymphocyte transformation was evaluated in the mitogen-induced blastogenesis assay. Both compounds were capable of inhibiting stimulation of B- and T-cell subsets by a
Isolation of a mycotoxin (roridin A) from Phomopsis spp.
D Samples et al.
Veterinary and human toxicology, 26(1), 21-23 (1984-02-01)
B Yagen et al.
Experientia, 43(8), 886-888 (1987-08-15)
Several trichothecene mycotoxins were shown to inhibit the growth of Saccharomyces cerevisiae. This effect was most pronounced with the macrocyclic trichothecenes, especially verrucarin A. Much less growth inhibition was observed with T-2 toxin. Verrucarol, diacetoxyscirpenol, acetyl T-2 toxin, HT-2 toxin
Kara N Corps et al.
Toxicologic pathology, 38(3), 429-451 (2010-05-01)
Macrocyclic trichothecene mycotoxins encountered in water-damaged buildings have been suggested to contribute to illnesses of the upper respiratory tract. Here, the authors characterized the adverse effects of repeated exposures to roridin A (RA), a representative macrocyclic trichothecene, on the nasal
S C Wilson et al.
International journal of toxicology, 24(3), 181-186 (2005-07-26)
The efficacy of chlorine dioxide (ClO2) in detoxifying two potential bioterrorism agents, the trichothecene mycotoxins verrucarin A and roridin A, was evaluated. In the first experiment, verrucarin A (1, 5, or 10 microg) and roridin A (5 or 10 microg)
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