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Safety Information

R4892

Sigma-Aldrich

Ranakinin

≥97% (HPLC)

Synonym(s):

Lys-Pro-Asn-Pro-Glu-Arg-Phe-Tyr-Gly-Leu-Met-NH2

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About This Item

Empirical Formula (Hill Notation):
C62H95N17O15S
CAS Number:
139446-71-2
Molecular Weight:
1350.59
MDL number:
MFCD00214390
UNSPSC Code:
12352200
PubChem Substance ID:
24899378

Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCC(O)=O)NC(=O)C3CCCN3C(=O)C(CC(N)=O)NC(=O)C4CCCN4C(=O)C(N)CCCCN)C(N)=O

Biochem/physiol Actions

NK1 tachykinin receptor agonist

Other Notes

Originally isolated from the brain of frog, Rana ridibunda

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

R4892-1MG:
R4892-.1MG:
R4892-VAR:
R4892-250UG:
R4892-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Badgery-Parker et al.
Peptides, 14(4), 771-775 (1993-07-01)
The tachykinin binding site preferences of neuropeptide gamma (NP gamma), its C-terminal fragments AcNP gamma(3-21), AcNP gamma(5-21), AcNP gamma(7-21), and AcNP gamma(9-21), other mammalian tachykinins, and the nonmammalian tachykinins ranakinin and carassin were examined in membrane binding competition studies. [125I]-Bolton-Hunter
F O'Harte et al.
Journal of neurochemistry, 57(6), 2086-2091 (1991-12-01)
An extract of the whole brain of the frog Rana ridibunda contained high concentrations of substance P-like immunoreactivity, measured with an antiserum directed against the COOH-terminal region of mammalian substance P and neurokinin B-like immunoreactivity, measured with an antiserum directed
M K Kodjo et al.
Endocrinology, 136(8), 3253-3259 (1995-08-01)
The adrenal gland of the frog is innervated by a network of fibers containing two tachykinins (ranakinin and [Leu3,Ile7]neurokinin A), which both stimulate corticosteroid secretion from frog adrenal tissue. The aim of the present study was to determine the mode
M K Kodjo et al.
The Journal of steroid biochemistry and molecular biology, 57(5-6), 329-335 (1996-03-01)
It has recently been shown that the adrenal gland of the frog Rana ridibunda is densely innervated by a network of fibers containing two novel tachykinins, i.e. ranakinin (the counterpart of substance P) and [Leu3, Ile7]neurokinin A. Both ranakinin and
Xiuhong Liu et al.
Journal of peptide science : an official publication of the European Peptide Society, 14(5), 626-630 (2007-11-13)
A bradykinin-like peptide has been isolated from the skin secretions of the frog Rana nigrovittata. This peptide was named ranakinin-N. Its primary structure, RAEAVPPGFTPFR, was determined by Edman degradation and mass spectrometry. It is structurally related to bradykinin-like peptides identified
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