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Safety Information

R4780

Sigma-Aldrich

RACK1 human

recombinant, expressed in E. coli, >90% (SDS-PAGE), buffered aqueous solution

Synonym(s):

Receptor for activated protein kinase C

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

recombinant

expressed in E. coli

Assay

>90% (SDS-PAGE)

form

buffered aqueous solution

mol wt

37 kDa

UniProt accession no.

P63244

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... GNB2L1(10399)

Biochem/physiol Actions

RACK1 (receptor of activated protein kinase C1) is an intracellular adapter protein, which belongs to a class of intracellular receptor proteins that bind activated members of the protein kinase C family. RACK1 serves as a scaffold protein for a wide range of kinases and membrane-bound receptors. RACK1 is a member of the tryptophane-aspartate (WD) family known for its propeller-like structure. Literature strongly indicates that RACK1 plays an important role in intracellular signaling at several functional levels. RACK1, a substrate for several kinases, is involved in the regulation of Src function and cell growth.
RACK1 is an intracellular receptor protein that binds activated members of the protein kinase C family.

Physical form

Supplied in a 0.2 μm filtered solution of 0.02 M Tris buffer, pH 8.0, with 0.15 M NaCl, 5 mM DTT, 0.1% CHAPS, and 30% glycerol (w/v).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

R4780-50UG:
R4780-BULK:
R4780-50UG-PW:
R4780-VAR:

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