Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

PZ0121

Sigma-Aldrich

CP-135807

≥98% (HPLC)

Synonym(s):

3-(N-Methylpyrrolidin-2R-ylmethyl)-5-(3-nitropyrid-2- yl)amino-1H-indole, 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-p yridinyl)-1H-indol-5-amine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C19H21N5O2
CAS Number:
151272-90-1
Molecular Weight:
351.40
MDL number:
MFCD00921453
UNSPSC Code:
51111800
PubChem Substance ID:
329823712
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +100 to +120°, c = 0.025 mg/mL in methanol

color

brown-red

solubility

DMSO: ≥5 mg/mL

storage temp.

room temp

SMILES string

CN1CCC[C@@H]1Cc2c[nH]c3ccc(Nc4ncccc4[N+]([O-])=O)cc23

InChI

1S/C19H21N5O2/c1-23-9-3-4-15(23)10-13-12-21-17-7-6-14(11-16(13)17)22-19-18(24(25)26)5-2-8-20-19/h2,5-8,11-12,15,21H,3-4,9-10H2,1H3,(H,20,22)/t15-/m1/s1

InChI key

YPFIYPNOWVPAPR-OAHLLOKOSA-N

Biochem/physiol Actions

CP-135807 is a selective 5-HT1D agonist.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

PZ0121-5MG:
PZ0121-25MG:
PZ0121-VAR:
PZ0121-BULK:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
060M4713

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Charlotte Ahlgren et al.
European journal of pharmacology, 499(1-2), 67-75 (2004-09-15)
The in vitro pharmacological properties of AR-A000002 ((R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide), a novel 5-hydroxytryptamine (5-HT)(1B) receptor antagonist, were studied. AR-A000002 bound with high affinity to guinea pig cortex and recombinant guinea pig 5-HT(1B) receptors (Ki=0.24 and 0.47 nM) and with 10-fold lower affinity
H Rollema et al.
Journal of neurochemistry, 67(5), 2204-2207 (1996-11-01)
In vivo microdialysis in guinea pig hypothalamus was used to study the effect of serotonin [5-hydroxytryptamine (5-HT)] subtype 1D autoreceptor blockade on the increase in extracellular 5-HT levels produced by a selective 5-HT reuptake inhibitor (SSRI). Administration of the selective

Articles

Serotonin Receptors

We offer many products related to serotonin receptors for your research needs.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service