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P7002

Sigma-Aldrich

Phospho(enol)pyruvic acid trisodium salt hydrate

≥97% (enzymatic), powder

Synonym(s):

2-(Phosphonooxy)-2-propenoic acid trisodium salt, PEP

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100 MG
¥10,850
250 MG
¥17,080
500 MG
¥32,340
1 G
¥55,510
5 G
¥187,600
25 G
¥714,000

¥10,850

List Price¥15,500Save 30%

In StockDetails

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100 MG
¥10,850
250 MG
¥17,080
500 MG
¥32,340
1 G
¥55,510
5 G
¥187,600
25 G
¥714,000

About This Item

Linear Formula:
C3H2O6PNa3 · x H2O
CAS Number:
5541-93-5
Molecular Weight:
233.99 (anhydrous basis)
MDL number:
MFCD00150734
UNSPSC Code:
12352204
PubChem Substance ID:
24898810
NACRES:
NA.32

¥10,850

List Price¥15,500Save 30%

In StockDetails

Product Name

Phospho(enol)pyruvic acid trisodium salt hydrate, ≥97% (enzymatic)

Quality Level

200

Assay

≥97% (enzymatic)

form

powder

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

[Na].OC(=O)C(=C)OP(O)(O)=O

InChI

1S/C3H5O6P.Na.H/c1-2(3(4)5)9-10(6,7)8;;/h1H2,(H,4,5)(H2,6,7,8);;

InChI key

KZPUEZVJSLLABH-UHFFFAOYSA-N

Application

Phospho(enol)pyruvic acid trisodium salt hydrate has been used in:
  • several enzyme activity assays, such as PRPP synthetase (PRPPS) assay[1], ribokinase (RK) assay[1], adenine phosphoribosyltransferase (APRT) assay[1]
  • in the reaction mixture for enzyme kinetic assay to determine platelet-derived growth factor receptor α (PDGFRA) kinetic parameters[2]
  • as a component in buffer B to react with adenosine diphosphate (ADP) to form adenosine triphosphate (ATP) for energy charge measurement[3]

Biochem/physiol Actions

Phosphoenolpyruvic acid plays a major role in the initial step of glycolysis by acting as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase.[4]
Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogenesis. In glycolysis, PEP is metabolized by pyruvate kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

P7002-VAR:
P7002-BULK:
P7002-5G:
P7002-25G:
P7002-250MG:
P7002-100MG:
P7002-1G:
P7002-500MG:
P7002-25MG:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL7776
BCCK8186
BCCG7369
BCCG0717
BCCF7058

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Kento Tokuyama et al.
Biotechnology and bioengineering, 115(6), 1542-1551 (2018-02-20)
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Casimir Ledoux Sofeu et al.
PLoS neglected tropical diseases, 12(9), e0006597-e0006597 (2018-09-07)
Canine rabies is endemic in Cameroon, but human rabies exposures and cases are likely underreported because of inadequate surveillance. In 2014, the surveillance network in the West region of Cameroon was reinforced by introducing a new anti-rabies center, a framework
Timothy R Rudd et al.
Faraday discussions, 218(0), 303-316 (2019-05-28)
A biological medicine (or biologicals) is a term for a medicinal compound that is derived from a living organism. By their very nature, they are complex and often heterogeneous in structure, composition and biological activity. Some of the oldest pharmaceutical
Deuterated nucleotides as chemical probes of RNA structure: a detailed protocol for the enzymatic synthesis of a complete set of nucleotides specifically deuterated at ribose carbons
Azad R, et al.
ScienceOpen Research (2015)
Energy metabolic state in hypothermically stored boar spermatozoa using a revised protocol for efficient ATP extraction
Nguyen QT, et al.
Biology Open, 5(11), 1743-1751 (2016)
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