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Safety Information

P5171

Sigma-Aldrich

Endoproteinase Arg-C from mouse submaxillary gland

Type XX-S, lyophilized powder, 250-800 units/mg protein (Lowry)

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About This Item

CAS Number:
82047-85-6
Enzyme Commission number:
3.4.21.35 (BRENDA, IUBMB)
EC Number:
279-893-6
MDL number:
MFCD01324999
UNSPSC Code:
12352204

type

Type XX-S

Quality Level

200

form

lyophilized powder

specific activity

250-800 units/mg protein (Lowry)

composition

Protein, 3.0-7.0%

analyte chemical class(es)

amino acids

storage temp.

2-8°C

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Unit Definition

One unit will hydrolyze 1.0 μmole of Nα-p-tosyl-L-arginine methyl ester per min at pH 8.0 at 25 °C.

Physical form

Lyophilized powder containing NaCl and sodium acetate

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H334,H335

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

P5171-25UN-C:
P5171-VAR:
P5171-25UN:
P5171-5UN:
P5171-100UN:
P5171-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
086K7680
061K7650
044K7650
028H7455
044K76501

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Ling Liu et al.
Biochemical and biophysical research communications, 407(2), 283-287 (2011-03-08)
Systemic or local delivery of human tissue kallikrein gene (hTK) has been shown to be an effective strategy to alleviate cerebral ischemia/reperfusion (I/R) injury, and tissue kallikrein (TK) administration can suppress glutamate- or acidosis-mediated neurotoxicity in vitro. In the present
Yoshika Yasuda et al.
Biological & pharmaceutical bulletin, 34(9), 1518-1521 (2011-09-02)
Oral formulation of tissue kallikrein consists primarily of porcine pancreatic kallikrein (PPK) and is used to improve peripheral circulation, menopausal symptoms, and impaired chorioretinal circulation. Although gastrointestinal absorption of tissue kallikrein after oral administration has been reported in nonclinical and
Waleska K Martins et al.
BMC medical genomics, 4, 76-76 (2011-10-29)
A wide variety of high-throughput microarray platforms have been used to identify molecular targets associated with biological and clinical tumor phenotypes by comparing samples representing distinct pathological states. The gene expression profiles of human cutaneous melanomas were determined by cDNA
Michael E Stern et al.
Investigative ophthalmology & visual science, 53(4), 2062-2075 (2012-03-08)
The purpose of this study was to determine if autoantibodies play a role in the immunopathogenesis of experimental dry eye disease. Dry eye was induced by exposing female C57BL/6 wild-type mice or hen egg lysozyme B-cell receptor transgenic mice to
Yi-Dong Wang et al.
European neurology, 65(4), 208-214 (2011-03-23)
Kallikrein, a serine proteinase, has been reported to have many functions, such as selectively dilating arterioles in the ischemic area and enhancing angiogenesis and neurogenesis. Therefore, it may promote cerebral poststroke reorganization. We observed the effect of human tissue kallikrein
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