P3662

Sodium pyruvate

Hybri-Max^™, powder, suitable for hybridoma

• Synonym(s): α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt
• Linear Formula: CH₃COCOONa
• CAS Number: 113-24-6
• Molecular Weight: 110.04
• Beilstein: 3568341
• EC Number: 204-024-4
• MDL number: MFCD00002586
• UNSPSC Code: 12352205
• PubChem Substance ID: 24898440
• NACRES: NA.75

Properties

• biological source: synthetic (organic)
• grade: Hybri-Max^™
• Assay: ≥99%
• form: powder
• technique(s): cell culture | hybridoma: suitable
• impurities: endotoxin, tested
• mp: >300 °C (lit.)
• solubility: H₂O: 100 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: [Na+].CC(=O)C([O-])=O
• InChI: 1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
• InChI key: DAEPDZWVDSPTHF-UHFFFAOYSA-M

Description

Application

Sodium pyruvate has been used as a component in maturation medium for oocyte evaluation.

Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Biochem/physiol Actions

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia. In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases. Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317,H319
• Precautionary Statements: P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Sens. 1B
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves