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Safety Information

N144

Sigma-Aldrich

Nitrendipine

>95%, powder

Synonym(s):

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester

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25 MG
¥11,550
100 MG
¥33,180
500 MG
¥154,700

¥11,550

List Price¥16,500Save 30%

Estimated to ship onMarch 20, 2025

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25 MG
¥11,550
100 MG
¥33,180
500 MG
¥154,700

About This Item

Empirical Formula (Hill Notation):
C18H20N2O6
CAS Number:
39562-70-4
Molecular Weight:
360.36
EC Number:
254-513-1
MDL number:
MFCD00082255
UNSPSC Code:
12352200
PubChem Substance ID:
24277857
NACRES:
NA.77

¥11,550

List Price¥16,500Save 30%

Estimated to ship onMarch 20, 2025

Request a Bulk Order

Quality Level

200

Assay

>95%

form

powder

color

yellow to green

solubility

methanol: 15 mg/mL
DMSO: 17.5 mg/mL
H2O: insoluble

SMILES string

CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC

InChI

1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3

InChI key

PVHUJELLJLJGLN-UHFFFAOYSA-N

Gene Information

human ... ADORA3(140) , CACNG1(786) , KCNH1(3756) , TTR(7276)
rat ... Adora1(29290) , Adora2a(25369)

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Biochem/physiol Actions

Ca2+ channel blocker; anti-hypertensive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

N144-500MG:
N144-VAR:
N144-25MG:
N144-BULK:
N144-100MG:

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Certificates of Analysis (COA)

Lot/Batch Number
028F08941
038H4745

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Felix Steger et al.
Radiation oncology (London, England), 7, 212-212 (2012-12-18)
5-Fluorouracil (5-FU) is an antimetabolite, which is frequently used as chemotherapeutic agent for combined chemoradiotherapy. The purpose of this study was to present the clinical course of three patients who developed severe cardiac toxicity by 5-FU and to give a
Dengning Xia et al.
Pharmaceutical research, 29(1), 158-169 (2011-07-13)
To investigate anti-solvent crystallization and growth mechanism of nitrendipine spherical crystals in an aqueous solution containing polymeric additives. Size and shape of crystals were investigated using laser diffractometry, optical microscopy and scanning electron microscopy (SEM). Crystalline form was determined by
Jian X Wu et al.
International journal of pharmaceutics, 433(1-2), 60-70 (2012-05-09)
This study focuses on the development of an automated image analysis method to extract information on nucleation and crystal growth from polarized light micrographs. Using the developed image analysis method, four parameters related to nucleation and crystal growth could be
Annik Bergeron et al.
Bioanalysis, 4(8), 897-908 (2012-04-27)
In the past several years, the impact of changing counter ions while keeping the same anticoagulant in bioanalytical LC-MS/MS methods has become a highly discussed topic. In order to confirm that there is no impact from counter ions, matrix effect
Peng Quan et al.
AAPS PharmSciTech, 12(4), 1136-1143 (2011-09-06)
The present investigation was undertaken with the objective of developing a solid formulation containing nitrendipine nanocrystals for oral delivery. Nitrendipine nanocrystals were prepared using a tandem precipitation-homogenization process. Then, spray drying, a cost-effective method very popular in industrial situations, was
View All Related Papers

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