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Safety Information

MSQC24

Sigma-Aldrich

SILu™Lite SigmaMAb Pembrolizumab Monoclonal Antibody

recombinant, expressed in CHO cells

Synonym(s):

Biologic Antibody Mimic, Biotherapeutic Antibody Mimic, Monoclonal Antibody Calibrator

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.24

recombinant

expressed in CHO cells

Quality Level

200

Assay

≥90% (HPLC)

form

solid

suitability

suitable for mass spectrometry

shipped in

wet ice

storage temp.

−20°C

General description

SigmaMAb Pembrolizumab (MSQC24) was designed to be a standard for the analysis of Pembrolizumab monoclonal antibodies using mass spectrometry. An isotopically labeled version is available as SILu™Mab Pembrolizumab (MSQC25).

SigmaMAb Pembrolizumab is for research use only and is not intended for diagnostic or therapeutic use.

Sequence

SigmaMAb Pembrolizumab Heavy Chain:
QVQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGGINPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRDYRFDMGFDYWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLG

SigmaMAb Pembrolizumab Light Chain:
EIVLTQSPATLSLSPGERATLSCRASKGVSTSGYSYLHWYQQKPGQAPRLLIYLASYLESGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHSRDLPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MSQC24-0.5MG:
MSQC24-PH:
MSQC24PROC:
MSQC24-VAR:
MSQC24-0.5MG-PW:
MSQC24-VAR-PW:
MSQC24-BULK:
MSQC24-BULK-N:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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