MAK551

Butyrylcholinesterase (BChE) Activity Assay Kit

sufficient for 100 colorimetric tests

• UNSPSC Code: 41116104
• NACRES: NA.21

Properties

• detection method: colorimetric
• relevant disease(s): endocrinological disorders, diabetes; obesity; cardiovascular diseases
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Butyrylcholinesterase (EC 3.1.1.8; BChE), also known as pseudocholinesterase or plasma cholinesterase, is mainly synthesized in liver and present in blood. BChE is a nonspecific cholinesterase enzyme and can hydrolyze many different choline esters, serving as the first line of defense against toxic compounds reaching the bloodstream. ​

The Butyrylcholinesterase Activity Assay Kit is based on a synthetic butyrylthiocholine based substrate, which can be hydrolyzed by BChE and produce thiocholine. Thiocholine can react with 5, 5′-dithiobis (2-nitrobenzoic acid) (DTNB) and generates a yellow chromophore that can be detected at 410 nm. The assay is convenient, sensitive and can detect as low as 6 mU/mL in a variety of samples.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H334
• Precautionary Statements: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3