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A continuous assay for peptide deformylase has been developed using a formylated dipeptide, formyl-Met-Leu-p-nitroanilide, as substrate. Removal of the formyl group by a peptide deformylase renders the dipeptide product, which contains a free NH2 terminus, a substrate for an aminopeptidase
Mitochondrial dysfunction has been implicated in cardiovascular diseases. Elevation of serum retinol binding protein 4 (RBP4) in patients has been linked to cardiovascular disease. However, the role of RBP4 on mitochondrial oxidative stress and vascular oxidative damage is not well
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