Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

M6684

Sigma-Aldrich

Anti-Matrix Metalloproteinase-24, Hinge Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-MMP-24, Anti-MT5-MMP

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD03097031
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen 65 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1:2,000

UniProt accession no.

Q9Y5R2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP24(10893)
mouse ... Mmp24(17391)

General description

Matrix metalloproteinase-24 (MMP-24) is expressed majorly in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.

Specificity

Reacts with reduced and native MMP-24. Recognizes the pro-form of MMP-24 as well as activation/breakdown products.

Immunogen

synthetic peptide corresponding to the hinge region of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5).

Biochem/physiol Actions

Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M6684-100UG:
M6684-VAR:
M6684-BULK:
M6684-100UG-PW:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
090K1566

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sol de la Peña et al.
Disease markers, 2014, 285906-285906 (2014-03-29)
During progression of gastric cancer (GC), degradation of the extracellular matrix is mediated by the matrix metalloproteases (MMPs) and their tissue inhibitors (TIMPs): changes in the expression of these have been related to unfavorable prognosis in GC. To analyze the
A M Romanic et al.
American journal of physiology. Renal physiology, 281(2), F309-F317 (2001-07-18)
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade the extracellular matrix (ECM). The membrane-type matrix metalloproteinases (MT-MMPs) are a new family of MMPs that differ from other MMPs in that they have a transmembrane domain that anchors
Heather H Ross et al.
FEBS letters, 581(30), 5923-5928 (2007-12-08)
Membrane-type 5 matrix metalloproteinase (MT5-MMP) expression is ubiquitous in brain development while restricted to regions of neuroplasticity in adult. In the multipotent NT2 model of neurogenesis and differentiation, MT5-MMP is differentially expressed with significantly higher mRNA levels in the differentiated
E Llano et al.
Cancer research, 59(11), 2570-2576 (1999-06-11)
A cDNA encoding a new member of the membrane-type (MT) matrix metalloproteinase (MMP) family has been identified and cloned from a human brain cDNA library. The isolated cDNA encodes a polypeptide of 645 amino acids that displays a similar domain

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service