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Safety Information

M3316

Sigma-Aldrich

Myoseverin B

≥97% (HPLC)

Synonym(s):

2,6-Bis(4-methoxybenzylamino)-9-cyclohexylpurine

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About This Item

Empirical Formula (Hill Notation):
C27H32N6O2
CAS Number:
361431-27-8
Molecular Weight:
472.58
MDL number:
MFCD08276922
UNSPSC Code:
12352200
PubChem Substance ID:
24724538
NACRES:
NA.77

Assay

≥97% (HPLC)

solubility

DMSO: soluble
H2O: insoluble

shipped in

dry ice

storage temp.

−20°C

SMILES string

COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C5CCCCC5)c4n2)cc1

InChI

1S/C27H32N6O2/c1-34-22-12-8-19(9-13-22)16-28-25-24-26(33(18-30-24)21-6-4-3-5-7-21)32-27(31-25)29-17-20-10-14-23(35-2)15-11-20/h8-15,18,21H,3-7,16-17H2,1-2H3,(H2,28,29,31,32)

InChI key

ZUZXYJOSNSTJMU-UHFFFAOYSA-N

Biochem/physiol Actions

Myoseverin, a new microtubule-binding molecule, acts reversibly on myoblast proliferation without the cytotoxic effects displayed by nonpurine-based microtubule-disrupting molecules, like taxol, vinblastine, nocodazole. Myoseverin can be effectively used for the inhibition of new vessel growth by inhibiting endothelial cell function and differentiation of progenitor cells.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M3316-5MG:
M3316-BULK:
M3316-1MG:
M3316-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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