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Safety Information

M3184

Sigma-Aldrich

MG 624

≥98%

Synonym(s):

N,N,N-Triethyl-2-(4-trans-stilbenoxy)ethylammonium iodide

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About This Item

Empirical Formula (Hill Notation):
C22H30INO
CAS Number:
77257-42-2
Molecular Weight:
451.38
MDL number:
MFCD00865233
UNSPSC Code:
12352200
PubChem Substance ID:
24278547
NACRES:
NA.77

Assay

≥98%

solubility

DMSO: ≤22 mg/mL
H2O: insoluble

storage temp.

2-8°C

SMILES string

[I-].CC[N+](CC)(CC)CCOc1ccc(cc1)\C=C\c2ccccc2

InChI

1S/C22H30NO.HI/c1-4-23(5-2,6-3)18-19-24-22-16-14-21(15-17-22)13-12-20-10-8-7-9-11-20;/h7-17H,4-6,18-19H2,1-3H3;1H/q+1;/p-1/b13-12+;

InChI key

RDTKUZXIHMTSJO-UEIGIMKUSA-M

Gene Information

human ... CHRNA7(1139)

Biochem/physiol Actions

Nicotinic acetylcholine receptor antagonist; selectively inhibits neuronal nicotinic α-bungarotoxin sensitive receptors that contain the α7 subunit.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

M3184-25MG:4548173996691
M3184-5MG:4548173996707
M3184-BULK:
M3184-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Glenn W Vicary et al.
Respiratory research, 18(1), 115-115 (2017-06-04)
Tobacco-related chronic lung diseases are characterized by alterations in lung architecture leading to decreased lung function. Knowledge of the exact mechanisms involved in tobacco-induced tissue remodeling and inflammation remains incomplete. We hypothesize that nicotine stimulates the expression of extracellular matrix
C Gotti et al.
British journal of pharmacology, 124(6), 1197-1206 (1998-08-28)
1. Starting from the structure of an old 4-oxystilbene derivate with ganglioplegic activity (MG624), we synthesized two further derivates (F2 and F3) and two stereoisomers of F3 (F3A and F3B), and studied their selective effect on neuronal nicotinic acetylcholine receptor

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