Skip to Content
Merck
All Photos(1)

Documents

Safety Information

M2381

Sigma-Aldrich

5-Methoxy-N,N-dimethyltryptamine

Synonym(s):

3-(2-Dimethylaminoethyl)-5-methoxyindole, 3-[2-(Dimethylamino)ethyl]-5-methoxyindole, 5-MeO-DMT, 5-Methoxy-DMT, 5-OMe-DMT

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C13H18N2O
CAS Number:
1019-45-0
Molecular Weight:
218.29
EC Number:
213-813-2
MDL number:
MFCD00005658
UNSPSC Code:
41116107
PubChem Substance ID:
24278119

drug control

USDEA Schedule I; Home Office Schedule 1; kontrollierte Droge in Deutschland

mp

69-70 °C (lit.)

storage temp.

2-8°C

SMILES string

COc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3

InChI key

ZSTKHSQDNIGFLM-UHFFFAOYSA-N

Gene Information

human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR5B(645694) , HTR6(3362) , HTR7(3363)
rat ... Htr1a(24473) , Htr2a(29595) , Htr2b(29581) , Htr2c(25187) , Htr7(65032)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Hallucinogen; non-selective serotonin receptor agonist.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H336

Hazard Classifications

STOT SE 3

Target Organs

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

JAN Code

M2381-50MG:
M2381-250MG:4548173309644
M2381-BULK:
M2381-VAR:
M2381-1G:4548173309637
M2381-5G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Thomas S Ray
PloS one, 5(2), e9019-e9019 (2010-02-04)
We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT(2A) (and possibly 5-HT(2C)) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are fairly selective for these two receptors. This manuscript is
Adam L Halberstadt
Pharmacology, biochemistry, and behavior, 143, 1-10 (2016-01-19)
Monoamine oxidase inhibitors (MAOIs) are often ingested together with tryptamine hallucinogens, but relatively little is known about the consequences of their combined use. We have shown previously that monoamine oxidase-A (MAO-A) inhibitors alter the locomotor profile of the hallucinogen 5-methoxy-N,N-dimethyltryptamine
Rafael Vitor Lima da Cruz et al.
Frontiers in molecular neuroscience, 11, 312-312 (2018-09-21)
The subgranular zone (SGZ) of dentate gyrus (DG) is one of the few regions in which neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in this region encode temporal information about partially overlapping contextual memories. The 5-Methoxy-N,N-dimethyltryptamine
Jessica Winne et al.
Experimental neurology, 326, 113175-113175 (2020-01-11)
Salicylate intoxication is a cause of tinnitus and comorbidly associated with anxiety in humans. In a previous work, we showed that salicylate induces anxiety-like behavior and hippocampal type 2 theta oscillations (theta2) in mice. Here we investigate if the anxiogenic
Vanja Dakic et al.
Scientific reports, 7(1), 12863-12863 (2017-10-11)
Dimethyltryptamines are entheogenic serotonin-like molecules present in traditional Amerindian medicine recently associated with cognitive gains, antidepressant effects, and changes in brain areas related to attention. Legal restrictions and the lack of adequate experimental models have limited the understanding of how
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service