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Safety Information

M0824

Sigma-Aldrich

MSSK1, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

MGC102944, SRPK3, STK23

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.32

recombinant

expressed in baculovirus infected Sf9 cells

Quality Level

200

product line

PRECISIO® Kinase

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

200-270 nmol/min·mg

mol wt

~98 kDa

UniProt accession no.

Q9UPE1

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... SRPK3(26576)

Biochem/physiol Actions

MSSK1, also known as SRPK3, is a muscle-specific protein kinase belonging to the serine arginine protein kinase family which phosphorylates serine/arginine repeat-containing proteins. Heart and skeletal muscle show high expression of the MSSK1/SRPK3 gene product. SRPK3-null mice display a new entity of type 2 fiber-specific myopathy with a marked increase in centrally placed nuclei. Transgenic mice overexpressing SRPK3 in skeletal muscle show severe myofiber degeneration and early lethality.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Cartagena Act

Cartagena Act Listed

JAN Code

M0824-10UG:
M0824-10UG-PW:
M0824-BULK:
M0824-VAR:

Certificates of Analysis (COA)

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Osamu Nakagawa et al.
Genes & development, 19(17), 2066-2077 (2005-09-06)
Myocyte enhancer factor 2 (MEF2) plays essential roles in transcriptional control of muscle development. However, signaling pathways acting downstream of MEF2 are largely unknown. Here, we performed a microarray analysis using Mef2c-null mouse embryos and identified a novel MEF2-regulated gene

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