L1415

L-162,313

≥95%, solid

• Synonym(s): 5,7-Dimethyl-2-ethyl-3-[[4-[2­(n-butyloxycarbonylsulfonamido)-5-isobutyl-3-thienyl]phenyl]methyl]imidazo­[4,5-b]­pyridine
• Empirical Formula (Hill Notation): C₃₀H₃₈N₄O₄S₂
• CAS Number: 151488-11-8
• Molecular Weight: 582.78
• MDL number: MFCD00915204
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278791

Properties

• Quality Level: 100
• Assay: ≥95%
• form: solid
• color: white
• solubility: DMSO: soluble 10 mg/mL
• originator: Merck & Co., Inc., Kenilworth, NJ, U.S.
• storage temp.: 2-8°C
• SMILES string: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c2ccc(Cn3c(CC)nc4c(C)cc(C)nc34)cc2
• InChI: 1S/C30H38N4O4S2/c1-7-9-14-38-30(35)33-40(36,37)29-25(17-24(39-29)15-19(3)4)23-12-10-22(11-13-23)18-34-26(8-2)32-27-20(5)16-21(6)31-28(27)34/h10-13,16-17,19H,7-9,14-15,18H2,1-6H3,(H,33,35)
• InChI key: RINPELQWLUGERM-UHFFFAOYSA-N
• Gene Information: human ... AGTR1(185) ; rat ... Agtr1(24180)

Description

Biochem/physiol Actions

Non-peptide AT₁ receptor agonist.

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves