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L0280

Sigma-Aldrich

Latex beads, amine-modified polystyrene, fluorescent blue

aqueous suspension, 2.0 μm mean particle size

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About This Item

MDL number:
MFCD00131492
UNSPSC Code:
12352116
NACRES:
NA.56

form

aqueous suspension

Quality Level

100

composition

Solids, 2.5%

technique(s)

cell based assay: suitable

mean particle size

2.0 μm

fluorescence

λex ~360 nm; λem ~420 nm

application(s)

cell analysis

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Application

Latex beads, amine-modified polystyrene, fluorescent blue has been used:
  • as inert beads to study the role of autophagy proteins in LC3-associated phagosome (LAP) maturation
  • in the culturing of peritoneal cells for phagocytic latex bead assay ex vivo
  • in the preparation of LAP stimuli coated beads

Biochem/physiol Actions

Polystyrene latex beads can be used to create latex agglutination systems. Polystyrene latex beads have been used to study the transmission of Mycobacterium leprae, the causative pathogen of leprosy, as well as to develop a method for mass screening for both pulmonary and extrapulmonary tuberculosis.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

L0280-BULK:
L0280-1ML:
L0280-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A C Perry et al.
Biology of reproduction, 60(3), 747-755 (1999-02-20)
To initiate normal embryonic development, an egg must receive a signal to become activated at fertilization. We here report that the ability of demembranated sperm heads to activate is abolished after incubation over the range 20-44 degreesC and is sensitive
R M Huebinger et al.
Virulence, 11(1), 695-706 (2020-06-04)
Surgical site infection risk continues to increase due to lack of efficacy in current standard of care drugs. New methods to treat or prevent antibiotic-resistant bacterial infections are needed. Multivalent Adhesion Molecules (MAM) are bacterial adhesins required for virulence. We
Jinming Yang et al.
Cancer research, 74(24), 7274-7284 (2014-10-23)
Myeloid cells are capable of promoting or eradicating tumor cells and the nodal functions that contribute to their different roles are still obscure. Here, we show that mice with myeloid-specific genetic loss of the NF-κB pathway regulatory kinase IKKβ exhibit
Sadayuki Hashioka et al.
Journal of Alzheimer's disease : JAD, 14(3), 345-352 (2008-07-05)
Microglial phagocytosis of amyloid-beta (Abeta) deposits is involved in Abeta clearance in vivo. To explore the ability of microglia to phagocytose beta, we cultured human microglia or human monocytic THP-1 cells directly on unfixed frontal cortex sections of an Alzheimer
Laure-Anne Ligeon et al.
Nature communications, 12(1), 1508-1508 (2021-03-10)
LC3-associated phagocytosis (LAP) contributes to a wide range of cellular processes and notably to immunity. The stabilization of phagosomes by the macroautophagy machinery in human macrophages can maintain antigen presentation on MHC class II molecules. However, the molecular mechanisms involved
View All Related Papers

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