Intended for use as general histological fixative. The addition of the eosin to the formulation allows the user to more easily visualize small fragments of tissue during the transfer of the tissue from the fixative to the tissue cassette.
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Archives of pathology & laboratory medicine, 135(5), 537-543 (2011-04-30)
While formalin fixation and paraffin embedding has become a universal mechanism of tissue preservation and a gold standard for immunohistochemistry, fixation and processing variables that may confound assay effectiveness have received little attention from the scientific community. To identify discrete
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 59(4), 356-365 (2011-03-18)
The loss of antigenicity in archival formalin-fixed paraffin-embedded (FFPE) tissue sections negatively affects both diagnostic histopathology and advanced molecular studies. The mechanisms underlying antigenicity loss in FFPE tissues remain unclear. The authors hypothesize that water is a crucial contributor to
Archives of pathology & laboratory medicine, 135(6), 744-752 (2011-06-03)
Formalin-fixed, paraffin-embedded tissue is the routine processing method for diagnostics practiced in pathology departments worldwide. To determine the potential value of non-cross-linking, formalin-free tissue fixation for diagnostics in pathology and proteomic investigations. We tested 3 commercially available, formalin-free tissue fixatives-FineFIX
The Journal of investigative dermatology, 137(3), 737-747 (2016-11-20)
Electrical stimulation (ES) is known to promote cutaneous healing; however, its ability to regulate reinnervation remains unclear. First, we show that ES treatment of human acute cutaneous wounds (n = 40) increased reinnervation. Next, to define neurophysiologic mechanisms through which ES
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