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E2006

Sigma-Aldrich

[D-Ala2]-Methionine enkephalinamide acetate salt

≥97% (HPLC)

Synonym(s):

Tyr-D-Ala-Gly-Phe-Met-NH2

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About This Item

Empirical Formula (Hill Notation):
C28H38N6O6S
CAS Number:
100929-50-8
Molecular Weight:
586.70
MDL number:
MFCD00133955
UNSPSC Code:
12352200
PubChem Substance ID:
329799024

Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(O)=O.CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(N)=O

InChI

1S/C28H38N6O6S.C2H4O2/c1-17(32-27(39)21(29)14-19-8-10-20(35)11-9-19)26(38)31-16-24(36)33-23(15-18-6-4-3-5-7-18)28(40)34-22(25(30)37)12-13-41-2;1-2(3)4/h3-11,17,21-23,35H,12-16,29H2,1-2H3,(H2,30,37)(H,31,38)(H,32,39)(H,33,36)(H,34,40);1H3,(H,3,4)/t17-,21+,22+,23+;/m1./s1

InChI key

CGDQCNFNHZVTLN-AUTZVVGKSA-N

Other Notes

Potent methionine enkephalin analog; resistant to enzymatic degradation

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

E2006-25MG:
E2006-VAR:
E2006-10MG:
E2006-5MG:
E2006-1MG:
E2006-50MG:
E2006-BULK:

Certificates of Analysis (COA)

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C B Pert et al.
Science (New York, N.Y.), 194(4262), 330-332 (1976-10-15)
[D-Ala2]-Met-enkephalinamide (DALA), a synthetic enkephalin analog designed by in vitro analysis, binds to opiate receptors almost as tightly as methionine-enkephalin. Since it is not susceptible to degradation by brain enzymes, low doses (5 to 10 micrograms) cause profound, long-lasting, morphine-like

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