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E1636

Sigma-Aldrich

β-Estradiol 3,17-disulfate dipotassium salt

≥95%

Synonym(s):

1,3,5(10)-Estratriene 3,17β-disulfate, 3,17β-Dihydroxy-1,3,5(10)-estratriene disulfate

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About This Item

Linear Formula:
C18H22O8S2K2
CAS Number:
17046-60-5
Molecular Weight:
508.69
MDL number:
MFCD00058502
UNSPSC Code:
51111800
PubChem Substance ID:
24894425
NACRES:
NA.77

biological source

synthetic

Assay

≥95%

form

powder

technique(s)

inhibition assay: suitable

solubility

water: 50 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

[K].[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24)OS(O)(=O)=O

InChI

1S/C18H24O8S2.K.H/c1-18-9-8-14-13-5-3-12(25-27(19,20)21)10-11(13)2-4-15(14)16(18)6-7-17(18)26-28(22,23)24;;/h3,5,10,14-17H,2,4,6-9H2,1H3,(H,19,20,21)(H,22,23,24);;/t14-,15-,16+,17+,18+;;/m1../s1

InChI key

CPIZVUIARARPNO-LBARCDFESA-N

Biochem/physiol Actions

Among other effects, this conjugated estrogen selectively inhibits glutathione S-transferases.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

E1636-25MG:
E1636-500MG:
E1636-50MG:
E1636-VAR:
E1636-100MG:
E1636-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The efficiencies for estrogen conjugate hydrolysis were compared between enzyme hydrolysis, acid solvolysis and a new method, ammonolysis. Samples included: 1) crystalline 1,3,5(10)-estratriene-3, 17 beta-diol disulfate (estradiol 3,17-disulfate), 2) squirrel monkey urine collected following an intravenous injection of [2,4,6,7-H] 1,3,5(10)-estratriene-3,17
Selective inhibition of glutathione S-transferases by 17 beta-estradiol disulfate.
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