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D9565

Sigma-Aldrich

β-Defensin 1 human

≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

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About This Item

MDL number:
MFCD01865661
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Assay

≥98% (HPLC and SDS-PAGE)

form

lyophilized powder (from 10 mM acetic acid)

mol wt

estimated mol wt 3.9 kDa

UniProt accession no.

P60022

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi
viruses

Mode of action

cell wall synthesis | interferes

storage temp.

−20°C

Gene Information

human ... DEFB1(1672)

Amino Acid Sequence

Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide bridges 5-34, 12-27, and 17-35]

General description

Chemical structure: peptide

Biochem/physiol Actions

A small cationic peptide which demonstrates anti-microbial activity. Originally isolated from human plasma, this substance is constitutively expressed in mucosal membrane epithelium.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

D9565-VAR:
D9565-5UG:
D9565-BULK:

Certificates of Analysis (COA)

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