Skip to Content
Merck
All Photos(1)

Key Documents

Safety Information

C8484

Sigma-Aldrich

Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone

solid, ≥90% (TLC)

Synonym(s):

Z-AEVD-FMK

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C28H39N4O10F
CAS Number:
Molecular Weight:
610.63
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Product Name

Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone, solid

Assay

≥90% (TLC)

Quality Level

form

solid

color

white

solubility

DMF: soluble

storage temp.

−20°C

SMILES string

COC(=O)CC[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF

InChI

1S/C28H39FN4O10/c1-16(2)24(27(39)32-20(21(34)14-29)13-23(36)42-5)33-26(38)19(11-12-22(35)41-4)31-25(37)17(3)30-28(40)43-15-18-9-7-6-8-10-18/h6-10,16-17,19-20,24H,11-15H2,1-5H3,(H,30,40)(H,31,37)(H,32,39)(H,33,38)/t17-,19-,20-,24-/m0/s1

InChI key

CHZRBQFKZDGMTP-CDSYHYPYSA-N

Amino Acid Sequence

Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK

Application

Caspase inhibitor.

Preparation Note

Prepare 20 mM stock solutions in dry DMSO to maintain product stability. Also soluble in DMF.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C8484-1MG:
C8484-VAR:
C8484-BULK:
C8484-1MG-PW:


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Remco van Horssen et al.
The Journal of biological chemistry, 284(3), 1620-1627 (2008-11-15)
ATP is the "principal energy currency" in metabolism and the most versatile small molecular regulator of cellular activities. Although already much is known about the role of ATP in fundamental processes of living systems, data about its compartmentalization are rather
Chetan V Aher et al.
Brain research bulletin, 81(1), 114-119 (2009-10-20)
Stressors evoke a well-studied physiological stress-response, namely, an immediate systemic release of catecholamines from the adrenals followed shortly afterwards by the release of adrenal steroids. The intensity of that response can often be inferred by the amount of adrenal steroids
J M Wood et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(7), 2065-2075 (2009-02-25)
Senile graying of human hair has been the subject of intense research since ancient times. Reactive oxygen species have been implicated in hair follicle melanocyte apoptosis and DNA damage. Here we show for the first time by FT-Raman spectroscopy in
Jeanine Marquet et al.
European journal of immunology, 40(9), 2557-2568 (2010-08-05)
MPhi and DC are key elements in the control of tissue homeostasis and response to insult. In this work, we demonstrate that MPhi and DC are the major producers of the phenylalanine catabolizing enzyme IL-4-induced gene 1 (IL4I1) under inflammatory
Stine C Klinger et al.
Journal of cell science, 124(Pt 7), 1095-1105 (2011-03-10)
Many different tissues and cell types exhibit regulated secretion of lipoprotein lipase (LPL). However, the sorting of LPL in the trans Golgi network has not, hitherto, been understood in detail. Here, we characterize the role of SorLA (officially known as

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service