Skip to Content
Merck
All Photos(1)

Documents

Safety Information

C2741

Sigma-Aldrich

Anti-CCR-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-C-C Chemokine Receptor 1

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD01864142
UNSPSC Code:
51111800
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

availability

not available in Japan

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5 μg/mL using human skeletal muscle, myocytes

UniProt accession no.

P32246

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CCR1(1230)
mouse ... Ccr1(12768)
rat ... Ccr1(57301)

Immunogen

synthetic peptide corresponding to the third extracellular loop of human C-C chemokine receptor 1 (CCR-1), conjugated to KLH. The immunizing peptide has 80% homology with the rat gene and 85% homology with the mouse gene.

Biochem/physiol Actions

CCR1 is a seven transmembrane protein that binds to macrophage inflammatory protein 1 alpha (MIP-1 alpha), monocyte chemoattractant protein 3 (MCP-3) and myeloid progenitor inhibitory factor-1 (MPIF-1). It has important role in protecting the host from inflammatory responses, viruses and parasites.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C2741-BULK:
C2741-50UL:
C2741-50UL-PW:
C2741-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J Hesselgesser et al.
The Journal of biological chemistry, 273(25), 15687-15692 (1998-06-23)
The CC chemokines macrophage inflammatory protein-1alpha (MIP-1alpha) and RANTES (regulated on activation normal T cell expressed) have been implicated in rheumatoid arthritis and multiple sclerosis. Since their effects are mediated through the CCR1 chemokine receptor, we set up a small

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service