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C2671

Sigma-Aldrich

Corticotropin Releasing Factor bovine

≥90% (HPLC), Synthetic

Synonym(s):

CRF, CRH

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About This Item

Empirical Formula (Hill Notation):
C206H340N60O63S
CAS Number:
92307-52-3
Molecular Weight:
4697.33
MDL number:
MFCD00081537
UNSPSC Code:
12352202
NACRES:
NA.32

Quality Level

200

Assay

≥90% (HPLC)

form

powder

UniProt accession no.

Q95MI6

storage temp.

−20°C

Gene Information

cow ... CRH(280755)

Amino Acid Sequence

Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Asn-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala

Biochem/physiol Actions

CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C2671-250UG:
C2671-VAR:
C2671-1MG-PW:
C2671-1MG:
C2671-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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In utero heat stress alters postnatal physiological and behavioral stress responses in pigs. However, the mechanisms underlying these alterations have not been determined. The study objective was to characterize the postnatal hypothalamic-pituitary-adrenal axis response of in utero heat-stressed pigs. Pigs
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Journal of cellular and molecular medicine, 20(2), 351-359 (2015-12-08)
Primary hyperparathyroidism (PHPT) is a common endocrine neoplastic disorder caused by a failure of calcium sensing secondary to tumour development in one or more of the parathyroid glands. Parathyroid adenomas are comprised of distinct cellular subpopulations of variable clonal status

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