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B1186

Sigma-Aldrich

Binucleine 2

≥97% (HPLC)

Synonym(s):

N′-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide

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About This Item

Empirical Formula (Hill Notation):
C13H11N5ClF
CAS Number:
220088-42-6
Molecular Weight:
291.71
MDL number:
MFCD00177827
UNSPSC Code:
12352200
PubChem Substance ID:
24724411
NACRES:
NA.77

Assay

≥97% (HPLC)

form

solid

solubility

DMSO: soluble >5 mg/mL
H2O: insoluble

storage temp.

2-8°C

SMILES string

CN(C)\C=N\c1c(cnn1-c2ccc(F)c(Cl)c2)C#N

InChI

1S/C13H11ClFN5/c1-19(2)8-17-13-9(6-16)7-18-20(13)10-3-4-12(15)11(14)5-10/h3-5,7-8H,1-2H3/b17-8+

InChI key

MNCYLHJHZOUDLB-CAOOACKPSA-N

Biochem/physiol Actions

Binucleine 2 is a cytokinesis inhibitor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

JAN Code

B1186-5MG:4548173225111
B1186-2MG:4548173225128
B1186-VAR:
B1186-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chantal Roubinet et al.
Current biology : CB, 31(18), 3973-3983 (2021-07-24)
Although nuclei are the defining features of eukaryotes, we still do not fully understand how the nuclear compartment is duplicated and partitioned during division. This is especially the case for organisms that do not completely disassemble their nuclear envelope upon

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