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Safety Information

AV44576

Sigma-Aldrich

Anti-MFAP3L antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Microfibrillar-associated protein 3-like, Anti-NYD-sp9

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

45 kDa

species reactivity

mouse, rat, horse, guinea pig, human, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_067679

UniProt accession no.

O75121

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MFAP3L(9848)

Immunogen

Synthetic peptide directed towards the N terminal region of human MFAP3L

Application

Anti-MFAP3L antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/ml.

Biochem/physiol Actions

Microfibrillar-associated protein 3-like (MFAP3L) is a protein kinase located primarily in the nucleus of the cells. Activated MFAP3L reportedly increases the invasion and metastasis of colorectal cancer cells.

Sequence

Synthetic peptide located within the following region: MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYY

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AV44576-100UL:
AV44576-100UG:

Certificates of Analysis (COA)

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Xiaomin Lou et al.
Biochimica et biophysica acta, 1842(9), 1423-1432 (2014-04-17)
An abundance of microfibril-associated glycoprotein 3-like (MFAP3L) significantly correlates with distant metastasis in colorectal cancer (CRC), although the mechanism has yet to be explained. In this study, we observed that MFAP3L knock-down resulted in reduced CRC cell invasion and hepatic

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