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Safety Information

93394

Sigma-Aldrich

Trizma® Buffer substance

pH 9.0

Synonym(s):

Tris Buffer substance, Tris(hydroxymethyl)aminomethane Buffer substance

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About This Item

MDL number:
MFCD00012590
UNSPSC Code:
12161700
PubChem Substance ID:
57653554

form

powder or crystals

mol wt

average mol wt 124.6

pH

8.7±0.1 (37 °C, 0.05 M)
9.0±0.1 (25 °C, 0.05 M)
9.6±0.1 (5 °C, 0.05 M)

solubility

H2O: 0.67 g/mL, clear, colorless

SMILES string

Cl.NC(CO)(CO)CO

InChI

1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChI key

QKNYBSVHEMOAJP-UHFFFAOYSA-N

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General description

Trizma® and its salts are used as biological buffers to control the pH of body fluids in vitro and in vivo. It acts as a precursor for polymers, oxazolones (with carboxylic acids), and oxazolidines (with aldehydes). Trizma can serve as an alkalizing agent in treating acidosis of the blood.

Application

Trizma® Buffer substance has been used as an eluent in asymmetrical flow field-flow fractionation (AFFFF).

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

93394-VAR:
93394-100G:
93394-25G:
93394-250G:
93394-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K Kolokassidou et al.
Journal of hazardous materials, 164(2-3), 442-447 (2008-09-20)
Disposed olive cake generates hydrophilic components that can be mobilized in the aquatic environment. This paper deals with the characterization of such components, isolated by alkaline extraction. It is shown that these substances possess properties very much resembling humic acid

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