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Safety Information

83263

Sigma-Aldrich

BICINE buffer Solution

BioUltra, for molecular biology, 1 M in H2O

Synonym(s):

N,N-Bis(2-hydroxyethyl)glycine

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About This Item

Empirical Formula (Hill Notation):
C6H13NO4
CAS Number:
150-25-4
Molecular Weight:
163.17
Beilstein:
1769362
MDL number:
MFCD00004295
UNSPSC Code:
12161700
eCl@ss:
32129211
PubChem Substance ID:
24888105

grade

for molecular biology

product line

BioUltra

concentration

1 M in H2O

impurities

DNases, none detected
 RNases, none detected
 phosphatases, none detected
 proteases, none detected

pH

5.0±0.2

density

1.05 g/mL at 20 °C

λ

neat

UV absorption

λ: 260 nm Amax: <0.07
λ: 280 nm Amax: <0.04

suitability

in accordance for filter test

SMILES string

OCCN(CCO)CC(O)=O

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

83263-500ML-F:
83263-100ML-F:
83263-BULK-F:
83263-1L-F:
83263-250ML-F:

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Certificates of Analysis (COA)

Lot/Batch Number
BCBH9508V
BCBG1799V
BCBG1799
BCBB4559V
BCBB4559

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S Ito et al.
Clinica chimica acta; international journal of clinical chemistry, 115(2), 135-144 (1981-09-10)
Serum guanase activity has been considered as a possible specific indicator of hepatocellular diseases. However, no suitable method is available for routine clinical determination of serum guanase activity. Conventional assay methods are troublesome and inaccurate, since guanine and 8-azaguanine, the
Raewyn M Town et al.
The journal of physical chemistry. A, 112(12), 2563-2571 (2008-03-04)
The impact of ligand protonation on the complexation kinetics of higher-order complexes is quantitatively described. The theory is formulated on the basis of the usual situation for metal complex formation in aqueous systems in which the exchange of water for
Dominik Koszel et al.
Journal of enzyme inhibition and medicinal chemistry, 27(2), 167-173 (2011-06-04)
A series of bis-N,N-(2-hydroxyethyl)glycine (bicine) derivatives, conjugated with an inhibitor of glucosamine-6-phosphate synthase, have been synthesized and their lipophilic and antifungal properties have been tested. The obtained compounds demonstrated higher lipophilicity than free inhibitor (FMDP) and, in consequence, an increased
Irradiation inactivation analysis of acetylcholinesterase and the effect of buffer salts.
D Parkinson et al.
Radiation research, 90(2), 252-259 (1982-05-01)
A Hausladen et al.
Archives of biochemistry and biophysics, 306(2), 415-419 (1993-11-01)
Xanthine oxidase has long been considered to be subject to inhibition by excess substrate. It is now shown that, although such inhibition can be seen in Tris or N,N-bis(2-hydroxyethyl)glycine buffers, earlier reports in which phosphate, pyrophosphate, or Veronal buffers were
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