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C1297

Sigma-Aldrich

Copper(II) sulfate

ReagentPlus®, ≥99%

Synonym(s):

Cupric sulfate

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About This Item

Linear Formula:
CuSO4
CAS Number:
7758-98-7
Molecular Weight:
159.61
EC Number:
231-847-6
MDL number:
MFCD00010981
UNSPSC Code:
12352302
PubChem Substance ID:
329774877
NACRES:
NA.21

vapor pressure

7.3 mmHg ( 25 °C)

product line

ReagentPlus®

Assay

≥99%

form

powder

reaction suitability

reaction type: click chemistry

pH

3.5-4.5 (20 °C, 50 g/L)

mp

200 °C (dec.) (lit.)

density

3.603 g/mL at 25 °C (lit.)

storage temp.

room temp

SMILES string

[Cu++].[O-]S([O-])(=O)=O

InChI

1S/Cu.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

InChI key

ARUVKPQLZAKDPS-UHFFFAOYSA-L

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General description

Copper(II)sulfate is a Lewis acid catalyst commonly used to promote acid-catalyzed organic transformations.

Application

Copper(II)sulfate can be used as a catalyst for the:
  • Alcoholysis of wheat straw into methyl levulinate.
  • Selective oxidation of amines to imines in the presence of hydrogen peroxide as an oxidant.
  • Synthesis of 1,2,3-triazoles via Click reactions of azides and alkynes.
  • Microwave-assisted Huisgen-type cycloaddition to synthesize modified poly(N-vinylpyrrolidone).

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H315,H319,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

C1297-500G:4548173190570
C1297-VAR:
C1297-BULK:
C1297-100G:4548173190563

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sofia Abassi et al.
Environmental toxicology, 34(9), 1013-1024 (2019-05-17)
The freshwater green algae Closterium ehrenbergii has been considered as a model for eco-toxicological assessment in aquatic systems. Heat shock proteins (HSPs) are a class of highly conserved proteins produced in all living organisms, which participate in environmental stress responses.
Marlize Z Bekker et al.
Journal of agricultural and food chemistry, 66(51), 13483-13491 (2018-12-13)
Diorganopolysulfanes can be generated when hydrogen sulfide (H2S) and thiols are oxidized in the presence of Cu(II) under conditions usually aimed at removing H2S from wine. This work sought to understand if polysulfanes could act as latent sources of H2S
William T Triplett et al.
Magnetic resonance in medicine, 72(1), 8-19 (2013-09-06)
The relationship between fat fractions (FFs) determined based on multiple TE, unipolar gradient echo images and (1) H magnetic resonance spectroscopy (MRS) was evaluated using different models for fat-water decomposition, signal-to-noise ratios, and excitation flip angles. A combination of single-voxel
Eleftherios A Makris et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(6), 2421-2430 (2013-03-05)
The objective of this study was to improve the biomechanical properties of engineered neotissues through promoting the development of collagen cross-links. It was hypothesized that supplementing medium with copper sulfate and the amino acid hydroxylysine would enhance the activity of
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