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04243

Sigma-Aldrich

Potassium phosphate monobasic

meets analytical specification of Ph. Eur., NF, E340, anhydrous, 98-100.5% (calc. to the dried substance)

Synonym(s):

Monopotassium phosphate, Potassium dihydrogen phosphate, prim.-Potassium phosphate

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About This Item

Linear Formula:
KH2PO4
CAS Number:
7778-77-0
Molecular Weight:
136.09
EC Number:
231-913-4
MDL number:
MFCD00011401
UNSPSC Code:
12161700
eCl@ss:
38070209
PubChem Substance ID:
329747897
NACRES:
NA.25

grade

anhydrous

Quality Level

200

Assay

98-100.5% (calc. to the dried substance)

form

crystalline

quality

meets analytical specification of Ph. Eur., NF, E340

impurities

org. volatile impurities, complies (GC)
 residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.04% KMnO4 red. matter (as O)
≤0.2% in water insoluble matters

loss

≤1% loss on drying, 130 °C

pH

4.2-4.5 (20 °C, 5%)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

mp

252.6 °C (lit.)

solubility

H2O: soluble 4.5 parts
alcohol: insoluble

density

2.338 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤10 mg/kg
fluoride (F-): ≤10 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤20 mg/kg
Fe: ≤10 mg/kg
Hg: ≤1 mg/kg
Na: ≤1000 mg/kg
Pb: ≤4 mg/kg
Zn: ≤20 mg/kg

suitability

complies for appearance of solution

SMILES string

[K+].OP(O)([O-])=O

InChI

1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

InChI key

GNSKLFRGEWLPPA-UHFFFAOYSA-M

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Application

Potassium phosphate monobasic was used for separating tobacco protein by using aqueous two-phase extraction.

Biochem/physiol Actions

Potassium phosphate monobasic also referred to as monopotassium phosphate or potassium dihydrogen phosphate is a soluble salt of potassium that serves as a buffering agent. It enhances the solubility of calcium and phosphorus in amino acid plus dextrose solutions and hence assists in improving the mineral balance of parenterally fed low birth weight infants.

Preparation Note

Potassium phosphate monobasic dissolves in 4.5 (approx.) parts of water to yield a solution. It is practically insoluble in alcohol.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

04243-4X5KG:
04243-500G:
04243-BULK:
04243-5KG:
04243-VAR:
04243-6X1KG:
04243-50KG-H:
2516162:
04243-1KG:
04243-6X500G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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P Chessex et al.
The Journal of pediatrics, 116(5), 765-772 (1990-05-01)
Because the monobasic potassium phosphate salt (monobasic) improves the solubility of calcium and phosphorus in amino acid plus dextrose solutions, compared with the current mixtures of monobasic plus dibasic salts (dibasic), we tested the bioavailability and clinical effects of monobasic
Deepa Balasubramaniam et al.
Journal of chromatography. A, 989(1), 119-129 (2003-03-19)
Tobacco has long been considered as a host to produce large quantity of high-valued recombinant proteins. However, dealing with large quantities of biomass is a challenge for downstream processing. Aqueous two-phase extraction (ATPE) has been widely used in purifying proteins
Casper Skovgaard et al.
Journal of applied physiology (Bethesda, Md. : 1985), 117(10), 1097-1109 (2014-09-06)
The purpose of this study was to examine whether speed endurance training (SET, repeated 30-s sprints) and heavy resistance training (HRT, 80-90% of 1 repetition maximum) performed in succession are compatible and lead to performance improvements in moderately trained endurance
Xinyan Wu et al.
Nature communications, 5, 4961-4961 (2014-09-24)
The PIK3CA gene is frequently mutated in human cancers. Here we carry out a SILAC-based quantitative phosphoproteomic analysis using isogenic knockin cell lines containing 'driver' oncogenic mutations of PIK3CA to dissect the signalling mechanisms responsible for oncogenic phenotypes induced by
Jesus Pacheco-Torres et al.
Nanomedicine : nanotechnology, biology, and medicine, 11(6), 1345-1354 (2015-04-19)
Liposomal drug delivery vehicles are promising nanomedicine tools for bringing cytotoxic drugs to cancerous tissues selectively. However, the triggered cargo release from liposomes in response to a target-specific stimulus has remained elusive. We report on functionalizing stealth-liposomes with an engineered
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