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SMB01334

Sigma-Aldrich

Daidzein glucuronide potassium salt

Synonym(s):

Daidzein 7-O-β-D-glucuronide potassium salt, Daidzein 7-O-glucuronide potassium salt, Daidzein-7-glucuronide potassium salt, Daidzin-7-O-glucuronide potassium salt

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About This Item

Empirical Formula (Hill Notation):
C21H17KO10
Molecular Weight:
468.45
UNSPSC Code:
12352205
NACRES:
NA.25

biological source

plant

Quality Level

200

Assay

≥95% (HPLC)

form

solid

mp

219—220 °C

storage temp.

2-8°C

General description

Daidzein-7-O-glucuronide is a conjugated polar metabolite of the soy isoflavone daidzein, present in blood and tissues following soy product consumption. Daidzein, circulating as its glucuronide or sulfate forms, influences various cellular processes and is utilized as a dietary supplement for addressing menopausal bone loss and cancer prevention. Recent studies have highlighted the importance of understanding the metabolism and disposition of isoflavones like daidzein and genistein in plasma, particularly regarding their role in preventing hormone-dependent diseases and their potential activation within target cells.

Application

Daidzein-7-O-glucuronide can be employed for studying the metabolism and metabolomic pathways of daidzein isoflavone, particularly in the context of metabolomics, phytochemical, and biochemical research.

Features and Benefits

Versatile and adaptable for a variety of research and metabolomics applications.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SMB01334-5MG:
SMB01334-BULK:
SMB01334-VAR:
SMB01334-1MG:

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Certificates of Analysis (COA)

Lot/Batch Number
0000291195
0000291195

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Juping Zhang et al.
Journal of agricultural and food chemistry, 66(49), 12941-12952 (2018-11-18)
Black soybeans are rich in isoflavones, which have several beneficial health effects. In this study, a validated method based on UHPLC-MS/MS was developed to screen black-soybean metabolites in rat urine, bile, and plasma and to quantify the compounds (daidzein, genistein
Sebastian T Soukup et al.
Archives of toxicology, 90(6), 1335-1347 (2016-02-04)
Soy isoflavones (IF) are in the focus of biomedical research since more than two decades. To assess their bioactivity, IF are investigated in rats and mice as a model. As the biological activity of IF is affected by their biotransformation
Amritha Johny et al.
Ecotoxicology and environmental safety, 197, 110611-110611 (2020-04-16)
Efficient aquaculture is depending on sustainable protein sources. The shortage in marine raw materials has initiated a shift to "green aquafeeds" based on staple ingredients such as soy and wheat. Plant-based diets entail new challenges regarding fish health, product quality

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