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S0200000

Salicylic acid

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Hydroxybenzoic acid

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About This Item

Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
69-72-7
Molecular Weight:
138.12
Beilstein:
774890
MDL number:
MFCD00002439
UNSPSC Code:
41116107
PubChem Substance ID:
329824417
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

API family

salicylic acid

manufacturer/tradename

EDQM

bp

211 °C (lit.)

mp

158-161 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Salicylic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

PHR1013

Salicylic acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1047

Phenol, Pharmaceutical Secondary Standard; Certified Reference Material

1609002

Salicylic acid, United States Pharmacopeia (USP) Reference Standard

Y0000405

Salicylic acid impurity B, European Pharmacopoeia (EP) Reference Standard

1524806

Phenol, United States Pharmacopeia (USP) Reference Standard

1609013

Salicylic acid Related Compound A, United States Pharmacopeia (USP) Reference Standard

1609024

Salicylic acid Related Compound B, United States Pharmacopeia (USP) Reference Standard

PHR1643

Salicylic Acid Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

BP775

Salicylic acid, British Pharmacopoeia (BP) Reference Standard

Signal Word

Danger

Hazard Statements

H302,H318,H361d

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

314.6 °F - closed cup

Flash Point(C)

157 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

S0200000-100MG:
S0200000:
S0200000-1EA:

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E Benfeldt et al.
Acta dermato-venereologica, 79(5), 338-342 (1999-09-24)
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given 2 g acetylsalicylic acid orally. Blood samples and dialysates from 4 microdialysis probes inserted
Tsung-Meng Wu et al.
Plant molecular biology, 83(4-5), 379-390 (2013-06-21)
Glutathione reductases (GRs) are important components of the antioxidant machinery that plants use to respond against abiotic stresses. In rice, one cytosolic and two chloroplastic GR isoforms have been identified. In this work, we describe the cloning and characterization of
Dorothea Ellinger et al.
Plant physiology, 161(3), 1433-1444 (2013-01-22)
A common response by plants to fungal attack is deposition of callose, a (1,3)-β-glucan polymer, in the form of cell wall thickenings called papillae, at site of wall penetration. While it has been generally believed that the papillae provide a
Yunlong Du et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7946-7951 (2013-04-25)
Removal of cargos from the cell surface via endocytosis is an efficient mechanism to regulate activities of plasma membrane (PM)-resident proteins, such as receptors or transporters. Salicylic acid (SA) is an important plant hormone that is traditionally associated with pathogen
S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous
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