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Safety Information

C2040

Supelco

Cloperastine hydrochloride

analytical standard

Synonym(s):

4-Chlorobenzhydryl 2-(1-piperidyl)ethyl ether

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About This Item

Empirical Formula (Hill Notation):
C20H24ClNO · HCl
CAS Number:
14984-68-0
Molecular Weight:
366.32
EC Number:
239-067-8
MDL number:
MFCD00079012
UNSPSC Code:
41116107
PubChem Substance ID:
329774924

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3

InChI

1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H

InChI key

UNPLRYRWJLTVAE-UHFFFAOYSA-N

Application

Cloperastine hydrochloride may be used as an analytical standard for the quantification of cloperastine in biological samples using liquid chromatography coupled to tandem mass spectrometry.[1]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C2040-10G:
C2040-1G:
C2040-BULK:
C2040-50G:
C2040-VAR:

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Certificates of Analysis (COA)

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[Clinical study of a new antitussive: cloperastine].
D Olivieri et al.
Archivio Monaldi per la tisiologia e le malattie dell'apparato respiratorio, 38(5-6), 209-218 (1983-09-01)
Gen Yamamoto et al.
Canadian journal of physiology and pharmacology, 87(11), 893-899 (2009-11-26)
We investigated the effects of the centrally acting antitussives dextromethorphan and cloperastine on urinary bladder dysfunction 24 h after cerebral infarction in rats using the cystometry technique. First, cystometrography was performed in conscious male Sprague-Dawley rats. Cerebral infarction was then
Antonia García et al.
Journal of pharmaceutical and biomedical analysis, 61, 230-236 (2012-01-10)
The classification of an impurity of a drug substance as genotoxic means that the "threshold of toxicological concern" (TTC) value of 1.5 μg/day intake, considered to be associated with an acceptable risk, should be the admissible limit in the raw
Nobuki Matsumoto et al.
Scientific reports, 11(1), 1492-1492 (2021-01-17)
Cancer therapy is often hampered by the disease's development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is responsible for
Cloperastine-based cough syrup and acute dystonic reactions.
Mercedes Serrano et al.
Developmental medicine and child neurology, 54(3), 287-287 (2012-02-14)
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