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Safety Information

A0500

Sigma-Aldrich

Acetamide

~99% (GC)

Synonym(s):

Amide C2

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About This Item

Linear Formula:
CH3CONH2
CAS Number:
60-35-5
Molecular Weight:
59.07
Beilstein:
1071207
EC Number:
200-473-5
MDL number:
MFCD00008023
UNSPSC Code:
12352111
PubChem Substance ID:
24278222
NACRES:
NA.77

biological source

synthetic

Quality Level

200

vapor pressure

1 mmHg ( 65 °C)

Assay

~99% (GC)

form

powder or crystals

bp

221 °C (lit.)

mp

78-80 °C (lit.)

solubility

water: 0.2 g/L, clear, colorless

SMILES string

CC(N)=O

InChI

1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)

InChI key

DLFVBJFMPXGRIB-UHFFFAOYSA-N

Gene Information

rat ... Ggt1(116568)

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General description

Acetamide based derivatives are potential anti-microbial, antifungal agents, used as disinfectants. Cigarette smoking triggers acetamide release. It is a minor by-product of paracetamol degradation. Acetamide is carcinogenic in rats.

Application

Acetamide has been used:
  • for the induction of recombinant protein in M. smegmatis
  • as a component of acetamide medium for fungal selection
  • in quenching experiment in mice tissue samples

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

A0500-500G:4548173926629
A0500-25G:
A0500-100G:4548173926605
A0500-BULK:
A0500-1G:4548173926612
A0500-50G:
A0500-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4162
BCCK4387
BCCH4504
BCCG3574
BCCF3542

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Gas chromatographic?mass spectrometric analysis of acrylamide and acetamide in cigarette mainstream smoke after on-column injection
Diekmann J, et al.
Journal of Chromatographic Science, 46(7), 659-663 (2008)
Synthesis of biologically active 2-chloro-N-alkyl/aryl acetamide derivatives
Katke SA, et al.
International Journal of Pharma Sciences and Research, 2, 148-156 (2011)
Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling
Verma M, et al.
Cell Stem Cell, 23(4), 530-543 (2018)
The RD1 proteins of Mycobacterium tuberculosis: expression in Mycobacterium smegmatis and biochemical characterization
Daugelat S, et al.
Microbes and Infection, 5(12), 1082-1095 (2003)
Maureen Hamilton et al.
Microbial cell factories, 19(1), 22-22 (2020-02-07)
Yarrowia lipolytica is an oleaginous yeast that can be genetically engineered to produce lipid and non-lipid biochemicals from a variety of feedstocks. Metabolic engineering of this organism usually requires genetic markers in order to select for modified cells. The potential
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