BioRenewable solvents are sourced from renewable and sustainable biobased materials, such as soy/palm oil, wood waste, hay or corn byproducts, etc. It is important to highlight that our BioRenewable products do not compete with food production.
920193
Cyrene™ 2-Methyltetrahydrofuran Blend
BioRenewable, DMF and NMP Substitute
Synonym(s):
2-MeTHF Solution, 2-Methyltetrahydrofuran solution, Cyrene solution
Sign Into View Organizational & Contract Pricing
All Photos(6)
Select a Size
Change View
100 ML
¥16,400
1 L
¥30,400
About This Item
Empirical Formula (Hill Notation):
C6H8O3
Molecular Weight:
128.13
UNSPSC Code:
12352212
NACRES:
NA.07
Recommended Products
form
liquid
contains
30-80 ppm BHT as stabilizer
greener alternative product characteristics
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
renewable carbon content
100%
density
1.153 g/mL
greener alternative category
, Aligned
General description
Cyrene™ 2-Methyltetrahydrofuran Blend with BHT as an inhibitor is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.
This Cyrene™ blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene™ nor 2-Methyltetrahydrofuran have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.
This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
This Cyrene™ blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene™ nor 2-Methyltetrahydrofuran have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.
This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is BioRenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.
Application
This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:
- HATU Amide Coupling - Replacement for DMF in amide and dipeptide coupling reactions
- Suzuki-Miyaura coupling reaction.
- Sonogashira coupling reaction.
- Reductive homocoupling reaction.
Features and Benefits
- Independently certified as 100% renewable carbon.
- Closer physical properties of NMP and DMF while maintaining high reaction yields.
- Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
- Both Cyrene and 2-MeTHF are also much safer for handling without the genotoxic concerns of other solvents.
- It has a lower viscosity than neat Cyrene making it more optimized for automated processes.
Legal Information
CYRENE is a trademark of Circa Group Pvt Ltd
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
JAN Code
920193-VAR:
920193-100ML:
920193-BULK:
920193-1L:
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Cyrene? blends: a greener solvent system for organic syntheses
Sullivan C, et al.
Green Chemistry, 24, 7184-7193 (2022)
Improved 2-pyridyl reductive homocoupling reaction using biorenewable solvent Cyrene?(dihydrolevoglucosenone)
Webb DA, et al.
RSC Sustainability, 1, 1522-1529 (2023)
Related Content
Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).
-
What is a BioRenewable solvent?
1 answer-
Helpful?
-
-
Why should you use BioRenewable solvents?
1 answer-
You will contribute to create a sustainable world, significantly lowering environmental impact. Biorenewable solvents also decrease petroleum sources dependency, have higher recovery rates, and/or are safer for handling and disposal.
Helpful?
-
-
Do BioRenewable solvents have a similar quality to petroleum-based solvents?
1 answer-
BioRenewable solvents can have the same or higher purity level compared to traditional solvents. These solvents are free of the many byproducts of petroleum manufacturing, such as benzene, aldehydes, and ethers.
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
