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Safety Information

45340

Sigma-Aldrich

(±)-Epichlorohydrin

purum, ≥99% (GC)

Synonym(s):

(±)-2-(Chloromethyl)oxirane, 1-Chloro-2,3-epoxypropane

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About This Item

Empirical Formula (Hill Notation):
C3H5ClO
CAS Number:
Molecular Weight:
92.52
Beilstein:
79785
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

3.2 (vs air)

Quality Level

vapor pressure

13.8 mmHg ( 21.1 °C)

grade

purum

Assay

≥99% (GC)

autoignition temp.

779 °F

expl. lim.

21 %

impurities

≤0.1% water

color

APHA: ≤20

refractive index

n20/D 1.438 (lit.)
n20/D 1.438

bp

115-117 °C (lit.)

mp

−57 °C (lit.)

density

1.183 g/mL at 25 °C (lit.)

application(s)

agriculture
environmental

storage temp.

room temp

SMILES string

ClCC1CO1

InChI

1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2

InChI key

BRLQWZUYTZBJKN-UHFFFAOYSA-N

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General description

(±)-Epichlorohydrin is an organochlorine compound, used in the manufacturing of epoxy resins, plasticizers, dye stuffs, lubricants, pharmaceuticals, adhesives and oil emulsification products.

Application


  • Pitfalls in the synthesis of fluorescent methotrexate oligopeptide conjugates.: Addresses challenges in synthesizing fluorescent methotrexate conjugates using Fmoc-Lys(Boc)-OH, aiming to optimize peptide-based drug delivery systems (Sebestyén et al., 2016).

  • Fluoreometric behavior of a novel bis-acridine orange bound to double stranded DNA.: Explores the fluorescent properties of a bis-acridine compound integrated with Fmoc-Lys(Boc)-OH for potential applications in DNA interaction studies (Takenaka et al., 2003).

  • Bis-naphthalene diimide exhibiting an effective bis-threading intercalating ability.: Investigates a bis-naphthalene diimide derivative, facilitated by Fmoc-Lys(Boc)-OH, demonstrating significant DNA intercalation, useful for gene therapy and molecular biology research (Nojima et al., 2003).

  • Novel synthesis of a tetra-acridinyl peptide as a new DNA polyintercalator.: Details the synthesis of a new DNA polyintercalator using Fmoc-Lys(Boc)-OH, highlighting its potential to enhance molecular diagnostics and therapeutic strategies (Ueyama et al., 2000).



Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Repr. 2 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

82.4 °F

Flash Point(C)

28 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 2 petroleums
Hazardous rank III
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

45340-500ML-F:4548173290942
45340-BULK-F:
45340-VAR-F:
45340-400L-KL-F:
45340-200L-KL-F:
45340-2.5L-F:4548173290935
45340-850L-DW-F:
45340-1L-F:4548173290928


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Synthesis of (R)-and (S)-epichlorohydrin.
Baldwin JJ, et al.
The Journal of Organic Chemistry, 43(25), 4876-4878 (1978)
Xing Xu et al.
Journal of colloid and interface science, 440, 219-228 (2014-12-03)
Amine-impregnated cotton stalk (AICS) prepared by the reaction of cotton stalk with epichlorohydrin, pyridine and trimethylamine was used as the effective adsorbent for perchlorate removal. Solid-state (13)C NMR spectra, FT-IR, BET principle and element analysis provided evidence that amine groups
Preparation and characterization of water soluble high molecular weight ?-cyclodextrin-epichlorohydrin polymers.
Renard E, et al.
European Polymer Journal, 33(1), 49-57 (1997)
Clinical Environmental Health and Toxic Exposures (2001)
Study of the crosslinking reaction between epichlorohydrin and starch.
Kuniak L and Marchessault RH.
Starch/Staerke, 24(4), 110-116 (1972)

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