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437638

Sigma-Aldrich

Tetrahydrofuran

≥99.0%, ACS reagent, contains 250 ppm BHT as inhibitor, suitable for HPLC

Synonym(s):

THF, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
109-99-9
Molecular Weight:
72.11
Beilstein:
102391
EC Number:
203-726-8
MDL number:
MFCD00005356
UNSPSC Code:
12352005
PubChem Substance ID:
329756392

product name

Tetrahydrofuran, contains 250 ppm BHT as inhibitor, ACS reagent, ≥99.0%

grade

ACS reagent

Quality Level

200

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

610 °F

contains

250 ppm BHT as inhibitor

expl. lim.

1.8-11.8 %

technique(s)

HPLC: suitable

impurities

≤0.015% peroxide (as H2O2)
≤0.05% water

evapn. residue

≤0.03%

color

APHA: ≤20

refractive index

n20/D 1.407 (lit.)

pH

~7

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

solubility

water: soluble

density

0.889 g/mL at 25 °C (lit.)

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Application

Tetrahydrofuran may be used used as a solvent in the following processes:
  • Formation of diacetylinic polymers.
  • RAFT polymerization of p-acetoxystyrene.
  • Synthesis of di-tert-butyl-Phosphinoferrocene.
  • Synthesis of n-TiO2-based amphiphilic polymer brushes.
It may be used in the following processes:
  • As mobile phase solvent in high-performance liquid chromatography.
  • As a solvent in the preparation of spin-coated poly(bisphenol A decane ether).
  • Formation of butyrolactone (BTL) by green oxidation method.
  • As a solvent for lignin depolymerization to isolate phenolic monomer.

Other Notes

Go to our Greener Alternative-2-Methyl Tetrahydrofuran - 155810

Go to our Greener Alternative-Cyclopentyl methylether - 675989

recommended

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-6.2 °F - closed cup

Flash Point(C)

-21.2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

437638-4X4L:4548173150260
437638-VAR:
437638-1L:
437638-16L:
437638-4L:
437638-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
SHBG1174V
SHBG9847V
SHBF7129V
SHBB3133V
SHBB2289V

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1,3 Dioxolane versus tetrahydrofuran as promoters for CO2-hydrate formation: Thermodynamics properties, and kinetics in presence of sodium dodecyl sulfate.
Torre JP, et al.
Chemical Engineering Science, 126, 688-697 (2015)
Novel Diacetylinic Aryloxysilane Polymers: A New Thermally Cross-Linkable High Temperature Polymer System.
Drake K, et al.
Macromolecules, 46(11), 4370-4377 (2013)
Oxidation of tetrahydrofuran to butyrolactone catalyzed by iron-containing clay.
Ausavasukhi A and Sooknoi T.
Green Chemistry, 17(1), 435-441 (2015)
Solène I Cauët et al.
Journal of polymer science. Part A, Polymer chemistry, 48(12), 2517-2524 (2010-07-27)
The kinetics of the RAFT polymerization of p-acetoxystyrene using a trithiocarbonate chain transfer agent, S-1-dodecyl-S'-(α,α'-dimethyl-α″-acetic acid)trithiocarbonate, DDMAT, was investigated. Parameters including temperature, percentage initiator, concentration, monomer-to-chain transfer agent ratio and solvent were varied and their impact on the rate of
Synthesis of NiO/TiO2 using amphiphilic diblock copolymer brushes (PMMA-b-PAA) by reversible addition fragmentation chain-transfer poltmerization.
Hojjati B and Charpentier PA.
Polymer Reviews, 50(2), 418-418 (2009)
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