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21069

Sigma-Aldrich

Calcium carbonate

tested according to Ph. Eur.

Synonym(s):

Calcii carbonas

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About This Item

Linear Formula:
CaCO3
CAS Number:
471-34-1
Molecular Weight:
100.09
Beilstein:
8008338
EC Number:
207-439-9
MDL number:
MFCD00010906
UNSPSC Code:
12352300
PubChem Substance ID:
329751908
NACRES:
NA.21

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

200

Assay

99.3%

form

powder

solubility

1 M acetic acid: soluble
alcohol: insoluble
hydrochloric acid: soluble (3 N)
nitric acid: soluble (2 N)

density

2.93 g/mL at 25 °C (lit.)

SMILES string

[Ca++].[O-]C([O-])=O

InChI

1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

InChI key

VTYYLEPIZMXCLO-UHFFFAOYSA-L

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Application

Calcium carbonate has been utilized by plants and animal for the formation of their skeletons and shells. It also facilitates the calcium carbonate crystal growth on a chitosan substrate.

Biochem/physiol Actions

Calcium carbonate is a naturally occurring compound that reduces T4 absorption and enhancess serum thyrotropin levels. It also precludes osteoporosis induced by thyrotropin-suppressive doses of levothyroxine in postmenopausal women. Additionally, it reduces diarrhea in individuals with protease inhibitor-induced HIV-infection.

Storage Class Code

13 - Non Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

21069-BULK:
21069-VAR:
21069-25KG:
21069-1KG:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL9366
BCCL4096
BCCK9782
BCCJ7525
BCCH8261

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Megan J Turner et al.
HIV clinical trials, 5(1), 19-24 (2004-03-06)
Although some evidence exists to support the practice of using calcium carbonate to treat nelfinavir-induced diarrhea, there is a lack of data supporting the role of calcium in diarrhea induced by other protease inhibitors (PIs). The objective of this prospective
F H Wilt
Journal of structural biology, 126(3), 216-226 (1999-09-04)
The endoskeletal spicules of sea urchin larvae are composed of calcite, a surrounding extracellular matrix, and small amounts of occluded matrix proteins. The spicules are formed by primary mesenchyme cells (PMCs) in the blastocoel of the embryo, where they adopt
N Singh et al.
JAMA, 283(21), 2822-2825 (2000-06-06)
The effect of calcium carbonate on the absorption of levothyroxine has not been studied systematically. Such a potential drug interaction merits investigation because concurrent treatment with both drugs is common, particularly in postmenopausal women. To investigate the potential interference of
Influence of the Chitosan Surface Profile on the Nucleation and Growth of Calcium Carbonate Films.
<BIG>Sukun Zhang</BIG>
Langmuir, 14, 6761-6766 (1998)
Alan T Marshall
Microscopy research and technique, 56(5), 341-357 (2002-03-06)
The Cnidaria are simple organisms that have remarkable physiological features susceptible to microscopic investigation. As a group they produce cnidae, the most complex intracellular organelles known, form symbioses with a range of unicellular algae, contain mucocytes that account for a
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