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SCT051

Sigma-Aldrich

BioTracker Carbon Monoxide Probe 1 Live Cell Dye

Live cell imaging dye for cellular carbon monoxide (CO), a cell signalling molecule implicated in vasodilation, neurotransmission, anti-inflammatory and anti-apoptotic processes.

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.47

form

lyophilized

detection method

fluorometric

General description

Carbon Monoxide (CO) is a colorless, odorless, tasteless gas that is highly toxic and lethal to mammals. However, there is growing evidence that CO can be endogenously produced in ourhuman body during the haem catabolism, and it was proved to be an important cell signaling molecule with substantial therapeutic potential protecting from vascular, inflammatory, or even cancer diseases. BioTracker Carbon Monoxide live cell dye is an allyl fluorescein ether-based probe for detecting CO in living cells. The dye is highly selective for CO and shows no effect with other analytes such as F-, Cl-, Br-, I-, AcO-, HCO3-, N3-, NO3-, SO42-, HSO4-, HSO3-, HS-, SCN-, CN-, ClO4-, IO4-, PO43-, and HPO42-, biothiols such as Cys, Hcy, and GSH, amino acids such as Ser, Trp, Ala,Phe, Gln, Glu, Lys, Leu, Gly, and Ile, and reactive oxygen/nitrogen species (ROS/RNS) such as ClO-, H2O2, NO2-, NO, HNO, ROO-, BuOO-, and -OH.
Spectral Properties:Excitation: 450- 480nm
Emission: 525 nm (Green)
Research Category:Live Cell Dye

Materials Required but Not Supplied:
  • PdCl2 (MilliporeSigma: Cat# 205885-1G or 520659-1G)
  • CROM-3 (MilliporeSigma Cat# SML0496-10mg), a carbon monoxide-releasing molecule
Important note: SCT051 staining works only in the presence of CROM-3 and PdCl2. Refer to product data sheet for more information.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SCT051:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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