All Photos(4)

Key Documents

COA/COQ

Safety Information

Safety & Regulatory

PYR0MATKIT

PyroMAT^® kit

Name: PyroMAT<SUP>®</SUP> kit
Brand: MM

Reagents and Interleukin-6 ELISA kit for Monocyte Activation Test (MAT), for Pyrogen testing

Sign Into View Organizational & Contract Pricing

All Photos(4)

About This Item

UNSPSC Code:

41116129

eCl@ss:

32160606

NACRES:

NA.74

Pricing and availability is not currently available.

Recommended Products

Slide 1 of 10

1 of 10

Sigma-Aldrich

ET0200

E-TOXATE^™ Kit

Sigma-Aldrich

E8029

E-Toxate^™ Endotoxin standard

Sigma-Aldrich

E8779

E-Toxate^™ reagent from Limulus polyphemus

Millipore

WBKLS

Immobilon Western Chemiluminescent HRP Substrate

Sigma-Aldrich

B8151

Scienceware^® biohazard disposal bags

Roche

CELLPRO-RO

Cell Proliferation Reagent WST-1

Sigma-Aldrich

383333

Tantalum(V) butoxide

Z740273

Aluminum heating/cooling block

Millipore

YT30142HW

Hazardous Waste Filtration System, 142 mm

Roche

11684302001

ABTS^™ Solution

Agency

EP Chapter 2.6.30

Quality Level

400

feature

ready-to-use

packaging

pkg of 1 kit

manufacturer/tradename

PyroMAT^®

application(s)

pharmaceutical
pyrogen testing

compatibility

configured for PyroMAT^®

shipped in

ambient

storage temp.

2-8°C

suitability

pyrogenic bacteria

Related Categories

Industrial Microbiology

Pyrogen Testing

General description

The PYROMAT^® System is a ready-to-use, in vitro solution for pyrogen testing, using the Monocyte Activation Test (MAT). It is based on the Mono-Mac-6 cell line and interleukin 6 (IL-6) read-out. The human monocytes that encounter pyrogens from contaminated sample, produce cytokines (IL-6), which can be detected with an enzyme-linked immunosorbent assay (ELISA). The kit contains the reagents needed to prepare the sample, perform the incubation with the monocytic cells, and the reagents needed for the ELISA detection.

Application

The PYROMAT^® System is used to ensure the safety of parenteral pharmaceutical products and medical devices.

Features and Benefits

Ready-to-use kit

Components

96-well plate, Endotoxin free water, RMPI culture medium
IL-6 ELISA kit and plate

Storage and Stability

2-8°C

Other Notes

Download the PyroMAT^® Method Software from here

Recommended products

To be used with PYROMAT^® cells (PYR0MATCELLS), Reference standard endotoxin (144.161.0001), NEP controls (MATHKSA, MATFLAGELLIN) and IL6 control (PYR0MATIL6)

Legal Information

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

comparable product

Product No.

Description

Pricing

control

Product No.

Description

Pricing

1.44161

Reference Standard Endotoxin, EDQM endotoxin standard for Monocyte Activation Test

PYR0MATIL6

PyroMAT^® Interleukin IL-6 standard, Interleukin-6 standard for use in the Monocyte Activation Test (MAT) for Pyrogen testing

MATFLAGELLIN

NEP Control Flagellin- PyroMAT^® System MAT, Non-endotoxin pyrogen control of flagellin for use in monocyte activation test

MATHKSA

NEP Control HKSA- PyroMAT^® System MAT, Non-endotoxin pyrogen control of heat killed Staphyloccus aureus for use in monocyte activation test

MATRESIQUIM0D

Resiquimod Non-Endotoxin Pyrogen (NEP) Control, for use with PyroMAT^®

MATFSL1

FSL-1 Non-Endotoxin Pyrogen (NEP) Control, for use with PyroMAT^®

MATPAM3CSK4

PAM3CSK4 Non-Endotoxin Pyrogen (NEP) Control, for use with PyroMAT^®

related product

Product No.

Description

Pricing

PYR0MATCELLS

PyroMAT^® cells, Cryopreserved MonoMac 6 cells for use in the Monocyte Activation Test (MAT) for Pyrogen testing, pkg of 2 vials

Pictograms

GHS08,GHS05,GHS07,GHS09

Signal Word

Danger

Hazard Statements

H290,H315,H317,H319,H360D,H411

Precautionary Statements

P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Repr. 1B - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.