MABN160

Anti-Syntenin-1 Antibody, clone 4F4.1

clone 4F4.1, 1 mg/mL, from mouse

• Synonym(s): Syntenin-1, Melanoma differentiation-associated protein 9, MDA-9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, TACIP18, Scaffold protein Pbp1, Syndecan-binding protein 1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 4F4.1, monoclonal
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_001007068
• UniProt accession no.: O00560
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SDCBP(6386)

Description

General description

The syndecans are transmembrane proteoglycans that place structurally heterogeneous heparan sulfate chains at the cell surface and a highly conserved polypeptide in the cytoplasm. Syntenin (also known as SDCBP) is an approximately 33 kDa scaffolding protein that that binds to kainate receptor subunits via a PDZ interaction. There is extensive colocalization of syntenin and kainate receptors with particularly intense labeling for both proteins at growth cones. It is proposed that syntenin has a role both in controlling membrane organization and in determining the formation and maturation of synapses.

Immunogen

GST-tagged recombinant protein corresponding to human Syntenin-1. The immunogen has a 98% homology to Mouse and Rat.

Application

Detect Syntenin-1 using this Anti-Syntenin-1 Antibody, clone 4F4.1 validated for use in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Syntenin-1 in 10 µg of HEK293 cell lysate.

Target description

~32 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable