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MAB858-3

Sigma-Aldrich

Anti-RSV Antibody, nucleoprotein, clone 130-12H

clone 130-12H, Chemicon®, from mouse

Synonym(s):

RSV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

300

antibody form

purified antibody

antibody product type

primary antibodies

clone

130-12H, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable

isotype

IgG2κ

shipped in

wet ice

General description

RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.

Specificity

Nuclear Protein, 42-44kD

Immunogen

CH-18537

Application

Anti-RSV Antibody, nucleoprotein, clone 130-12H detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA & IF.
ELISA at 1:800+

Indirect Immunofluorescence at 1:100-200+ (fresh frozen tissue sections)

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Purified. Liquid 0.02M PB, 0.25M NaCl, Ph 7.6 0.1% sodium azide.

Storage and Stability

Store at 2-8°C

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB858-3:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Julien Sourimant et al.
Science advances, 8(25), eabo2236-eabo2236 (2022-06-25)
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory infections in infants and the immunocompromised, yet no efficient therapeutic exists. We have identified the AVG class of allosteric inhibitors of RSV RNA synthesis. Here, we demonstrate through biolayer
Silke M Currie et al.
Journal of immunology (Baltimore, Md. : 1950), 196(6), 2699-2710 (2016-02-14)
Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infection in infants, causing significant morbidity and mortality. No vaccine or specific, effective treatment is currently available. A more complete understanding of the key components of effective host response
Shuai Shao et al.
NPJ vaccines, 9(1), 62-62 (2024-03-20)
Respiratory syncytial virus (RSV) is one of the most important pathogens causing respiratory tract infection in humans, especially in infants and the elderly. The identification and structural resolution of the potent neutralizing epitopes on RSV fusion (F) protein enable an
Cholesterol-rich microdomains as docking platforms for respiratory syncytial virus in normal human bronchial epithelial cells.
San-Juan-Vergara, H; Sampayo-Escobar, V; Reyes, N; Cha, B; Pacheco-Lugo, L; Wong et al.
Journal of virology null

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