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Safety Information

MAB1962

Sigma-Aldrich

Anti-Integrin β2 Antibody, clone P4H9

clone P4H9, Chemicon®, from mouse

Synonym(s):

CD18

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Pricing and Inventory is not available. Please check the Merck website for more information.

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

P4H9, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG3

NCBI accession no.

NM_000211.2

UniProt accession no.

P05107

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB2(3689)

Specificity

beta2 integrin on hematopoeitic cells. Not present on platelets, endothelial cells, epithelial cells or fibroblasts.

Application

Detect Integrin β2 using this Anti-Integrin β2 Antibody, clone P4H9 validated for use in IH.
Research Category
Cell Structure
Research Sub Category
Integrins
Suitable for use in immunofluorescence at 1:1000.

Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.

For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.

Physical form

Format: Purified
Non-sterile buffer of 0.02M phosphate, 0.25M Sodium Chloride, pH 7.6,

0.1% sodium azide.

Storage and Stability

Maintain between 2 and 8°C.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB1962:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elzbieta Pluskota et al.
The Journal of biological chemistry, 279(17), 18063-18072 (2004-02-11)
Plasmin, the pivotal thrombolytic enzyme, is generated on the surface of many cell types, where urokinase receptor (uPAR)-bound urokinase (uPA) activates cell-bound plasminogen (Plg). It has been reported that neutrophils mediate endogenous thrombolysis involving a uPA-dependent mechanism, and we previously
Elzbieta Pluskota et al.
Blood, 101(4), 1582-1590 (2002-10-24)
Previous studies demonstrated that integrin alpha(M)beta(2) (CD11b/18, Mac-1) forms a physical complex with the urokinase-type plasminogen activator receptor (uPAR/CD87) on leukocytes. In this study, we used human peripheral blood neutrophils and transfected cells expressing alpha(M)beta(2), uPAR, or both receptors to
I N Gavrilovskaya et al.
Journal of virology, 73(5), 3951-3959 (1999-04-10)
Hantaviruses replicate primarily in the vascular endothelium and cause two human diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). In this report, we demonstrate that the cellular entry of HFRS-associated hantaviruses is facilitated by specific integrins
Yukinori Endo et al.
Cell adhesion & migration, 12(2), 93-100 (2016-10-08)
Anosmin is an extracellular matrix protein, and genetic defects in anosmin result in human Kallmann syndrome. It functions in neural crest formation, cell adhesion, and neuronal migration. Anosmin consists of multiple domains, and it has been reported to bind heparan
Chia-Hsiang Yen et al.
Marine drugs, 17(12) (2019-11-28)
Chitosan is sensitive to environmental pH values due to its electric property. This study investigates whether the pH-responsive chitosan assay can provide a simple method to evaluate the aggressive behavior of cancer cells with cell detachment ratio. The epithelial-mesenchymal transition
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