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MAB1476

Sigma-Aldrich

Anti-Chymotrypsin Antibody, Human Pancreas

ascites fluid, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable

isotype

IgG3

NCBI accession no.

NM_001907.1

UniProt accession no.

P40313

shipped in

dry ice

target post-translational modification

unmodified

General description

Chymotrypsin is an intestinal proteolytic enzyme composed of three polypeptide chains. It is produced in the pancrease as the inactive form chymotrypsinogen (single 245 aa chain). Chymotrypsinogen is activated in the duodenum by trypin and other active chymotrypsin molecules. It preferentially catalyzes the hydrolysis of peptide bonds involving L-isomers of tyrosine, phenylalanine and tryptophan. It also readily acts upon amides and esters of susceptible amino acids. Chymotrypsin catalyzes the hydrolysis of bonds of leucyl, methionyl, asparaginyl and glutamyl residues.

Specificity

Recognizes chymotrypsin.

Immunogen

Purified human pancreatic chymotrypsin.

Application

Detect Chymotrypsin using this Anti-Chymotrypsin Antibody, Human Pancreas validated for use in ELISA, IH.
ELISA

Immunohistochemistry: 1:1000.

Optimal working dilution must be determined by the end user.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry

Physical form

Liquid. Contains no preservative.

Storage and Stability

Maintain at -20°C in convenient aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB1476:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Syairah Hanan Shaharuddin et al.
Frontiers in cellular and infection microbiology, 11, 678482-678482 (2021-07-21)
COVID-19 pandemic has infected more than 154 million people worldwide and caused more than 3.2 million deaths. It is transmitted by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and affects the respiratory tract as well as extra-pulmonary systems, including
Carlie S Sigel et al.
Cancer cytopathology, 121(8), 459-470 (2013-02-15)
Acinar cell neoplasms of the pancreas are rare but when encountered, the diagnosis is often established based on cytology specimens. Diagnostic accuracy is important because acinar cell carcinomas are aggressive yet may mimic tumors with different outcomes and management. The
Markus Breunig et al.
Cell stem cell, 28(6), 1105-1124 (2021-04-30)
Personalized in vitro models for dysplasia and carcinogenesis in the pancreas have been constrained by insufficient differentiation of human pluripotent stem cells (hPSCs) into the exocrine pancreatic lineage. Here, we differentiate hPSCs into pancreatic duct-like organoids (PDLOs) with morphological, transcriptional, proteomic

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