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Safety Information

CC1057

Sigma-Aldrich

MMP-7, human, recombinant

Synonym(s):

Pro-matrilysin

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.77

biological source

human

Assay

~70% (followed by staining with CBB R-250, SDS-PAGE)

form

liquid

specific activity

5453 U/mg

manufacturer/tradename

Chemicon®

concentration

0.1 mg/mL

NCBI accession no.

NM_002423.3

UniProt accession no.

P09237

shipped in

dry ice

General description

MOLECULAR WT:

28,924 Daltons calculated from primary amino acid sequence.
Product Source: Recombinant from E. Coli

Linkage

Replaces: AG905

Unit Definition

Specific Activity: One unit of enzyme activity is defined as the digestion of 1 micro g of Azocoll/min.at pH 7.5 and 37°C acetate.

Physical form

Solution in 25 mM Tris-HCl (pH 7.5), 5 mM CaCl2, 0.15 M NaCl, 0.01% Brij35 0.02% NaN3

Storage and Stability

Maintain at -80ºC for up to one year from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

CC1057:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sergey Filippov et al.
The Journal of experimental medicine, 198(6), 925-935 (2003-09-10)
Human macrophages found in juxtaposition to fragmented elastin in vivo express the elastolytic matrix metalloproteinases (MMPs) progelatinase B, prometalloelastase, and promatrilysin. Though MMPs can degrade a range of extracellular matrix components, increasing evidence suggests that preferred targets in vivo include

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