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Safety Information

AP505F

Sigma-Aldrich

Goat Anti-Human Ig κ chain Antibody, FITC conjugate

Chemicon®, from goat

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

goat

Quality Level

100

conjugate

FITC conjugate

antibody form

affinity purified immunoglobulin

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

shipped in

wet ice

target post-translational modification

unmodified

Related Categories

General description

Antibody molecules typically comprise two immunoglobulin light chains covalently bound to a pair of heavy chains. Immunoglobulin light chains occur in two types, designated by the Greek letters kappa and lambda. Kappa and lambda light chains are approximately 250 amino acids in length with an average mass of about 25 kDa. The ratio of kappa to lambda found in the immunoglobulin population varies by species.

Specificity

Reacts with human kappa light chains. Absorbed for human myeloma proteins with λ light chains.

Application

Immunofluorescence: ≤1 μg/106 cells.

Optimal working dilutions must be determined by the end user.
This Goat anti-Human Ig κ chain Antibody, FITC conjugate is validated for use in IF for the detection of Human Ig κ chain.

Physical form

Purified by affinity chromatography on pooled human Igs with kappa light chains covalently linked to agarose. Liquid in 1.0 mL PBS/NaN3.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AP505F:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Joel G Turner et al.
Oncotarget, 7(48), 78896-78909 (2016-11-03)
Acquired proteasome-inhibitor (PI) resistance is a major obstacle in the treatment of multiple myeloma (MM). We investigated whether the clinical XPO1-inhibitor selinexor, when combined with bortezomib or carfilzomib, could overcome acquired resistance in MM. PI-resistant myeloma cell lines both in

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